F********g
发帖数: 38 | 1 你老板当时真的相信这种idea吗？ 做出来之后和做出来之前，你的看法会截然不同。
就像楼上几位讲的，绝大多数人可能会有一闪而过的念头，但少了股蛮劲儿。 |
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J********3
发帖数: 3151 | 2 俺老板属于那种为科学可以献身的那种，觉得俺老板可能信了，我们暗地里做了些技术
、人员、试剂等储备，不像俺就当耳旁风了。 |
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n*********b
发帖数: 140 | 3 The idea was likely conceived while Yamanaka was still in UCSF. He was
lucky to hire this new postdoc who was new to the field and was persistent.
Lesson #1: test your bold idea as soon as you start your independent career.
Lesson #2: hire a yes-man/woman to work on your risky project. |
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f*******e
发帖数: 354 | 4 他用这个idea骗的postdoc，但是他自己讲到过是他的postdoc提议一堆病毒一起上，而
不是挑几个组合一下。所以postdoc也是个猛男，大部分人会吓到 |
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Z**S
发帖数: 1211 | 6 I thought the top 20 candidates were from micro array comparison studies. |
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o**4
发帖数: 35028 | 7 应该不是的，是依靠常识，需要大量知识，然后用microarray的结果作参照选出来的 |
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l***d
发帖数: 1828 | 8 怀疑你们真的是做ips的吗?ips的来龙去脉听听几年前Yamanaka在NIH的报告就一清二楚
了,那个一作博士后其实是他的PhD学生,本来做别的课题,后来留在自己实验室做博士后
接这个ips的课题,另外一个学生做不下去,走了,这个接手的一作博士后07的human ips
也是一作,我个人觉得其实两人可以share的 |
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M*****n
发帖数: 16729 | 10 very good points!
career. |
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Z**S
发帖数: 1211 | 12 How do you know if it was not the reverse, that he picked the top
candidates from the microarray comparison, then used 常识 to weed
out the most obvious. That would make a lot of sense. |
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k*****1
发帖数: 454 | 13 正解。他在卡罗林斯卡作报告的时候也这么说的，还说自己很对不起那个学生。当时全
场掌声 |
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Z**********g
发帖数: 222 | 14 Mark.
Reprogramming Energy Metabolism已经被Weinberg归纳为肿瘤emerging Hallmark了。 |
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Z**********g
发帖数: 222 | 15 Mark.
Reprogramming Energy Metabolism已经被Weinberg归纳为肿瘤emerging Hallmark了。 |
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i*****i
发帖数: 154 | 17 (Cancer Cell, 3, 219–231, March 2003)
We recently were made aware of a number of errors that were made in the
processing/compiling of data figures in this paper. Although we stand by the
conclusions of the paper and intend to provide support for them in future
publications, the inappropriate presentation did not and does not fall
within the bounds of acceptable scientific practice. Accordingly, we are
retracting the paper in its entirety. We apologize for any inconvenience
this may have caused.
... 阅读全帖 |
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q******g
发帖数: 3858 | 21 最后一句话啥意思？真的找不到Yi-Ning Cheng， 还是暗示他出的错误？ |
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r**b
发帖数: 143 | 22 做cancer的人大部分都读过他的一篇review：The hallmarks of cancer |
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l**********1
发帖数: 5204 | 23 she is as 1000 tallent now in tg/wan wan already ? !!
from
HTTP : //www.sciencedirect.com/science/article/pii/S1535610803000308
and
Cancer Cell Elsevier
www.elsevier.com/journals/cancer-cell/1535-6108Cancer Cell publishes reports
of novel results in any area of cancer research, from molecular and
cellular biology to clinical ...
5 year impact factor: 28.17
HTTP : //www.google.co.uk/search?hl=en&tbo=d&output=search&sclient=psy-ab&q=
cancer+cell+impact+factor+&btnK= |
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Z******5
发帖数: 435 | 24 谷歌学术显示被引用298次了~~~
现在看不了全文啊~~~ |
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l**********1
发帖数: 5204 | 25 en
那个298 >0.6 positive citations 全是骗纺锭地 too ?!! |
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y***k
发帖数: 60 | 27 看了下paper，很明显Fig1C、Fig2A、Fig3D、Fig4A里面的RAS是一样的...
这造假也造的太简单粗暴了，唉 |
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c*******4
发帖数: 7 | 28 引用这东西有时候也很盲目
看这篇都已经98次了
http://www.ncbi.nlm.nih.gov/pubmed/21336307
很神奇的光 online “Erratum” 就两次
WB翻来翻去 ps
最后也是重新补个真真假假的图
“We apologize for these serious mistakes. The original conclusions of the
paper are unchanged.”
要是老板没影响力，估计早撤稿了 |
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b**********8
发帖数: 349 | 30 啊，还以为他是华人老板中比较牛的呢？难道名声不好？ |
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l**********1
发帖数: 5204 | 31 几乎清一色 非白人/美犹的东亚裔作者名单 不说明了 lab 工作语言是粤语or 普通话
or 棒子语吧
尽管纺锭是NIH的.... Lol
Chang CJ, Chao CH, Xia W, Yang JY, Xiong Y, Li CW, Yu WH, Rehman SK, Hsu JL,
Lee HH, Liu M, Chen CT, Yu D, Hung MC.
Source
Nat Cell Biol. 2011 13: 317-
p53 regulates epithelial-mesenchymal transition and stem cell properties
through modulating miRNAs. |
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c********6
发帖数: 189 | 33 牛 is not equal to good personality and reputation. |
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s*****g
发帖数: 7857 | 34 是啊,芳鼎骗到手,也花完了,也交差了,你奈我何? |
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c****z
发帖数: 299 | 36 不要这么轻易猜测同胞嘛，说不定真的是联系不上了，大家找找现在这个作者在哪 |
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x******h
发帖数: 838 | 37 古狗了一下，她当时是小本，现在可能是儿科医生。就算她动手做的，把主要责任放在
一个小本身上也是不合适的。 |
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l**********1
发帖数: 5204 | 38 Also one quasi-professional tenis player while she was at MIT campus.
cited
>Women’s Tennis Wins NEWMAC Championship
MIT SWEEPS BABSON, DEFEATS MOUNT HOLYOKE AND WELLESLEY TO CLINCH TITLE
By Nisha Singh
TEAM CO-CAPTAIN
xxxxx ignored
The third doubles team of Nisha Singh ’00-Yi-Ning Cheng ’02 didn’t lose
a game, winning 8-0.
HTTP: //tech.mit.edu/V119/N52/52wtennis.52s.html |
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c****z
发帖数: 299 | 40 ╮(╯▽╰)╭~~
老老实实勤勤恳恳的同学绝大部分都演变成了千老、高级技术员；玩把戏的发了大文章
、捞到好位置，拿到funding，生活滋润，被人揪出来的好像也没有什么后果，小部分
负责的老板还主动retract一下，大部分打死不承认找个理由搪塞过去了
世界真是不公 |
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L*****C
发帖数: 157 | 42 I am thinking about setting up Western blotting in my lab. Any suggestion on
how to prevent "ps" happening? Run triplicates? Verifying with other
techniques (e.g. RT-PCR)? |
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c****z
发帖数: 299 | 45 发文章前把关，每一条WB data出示full length blots的原始图片，即使杂志不要求，
也实验室留底。还有就是cell line的实验，我觉得少说得重复个两三次吧。
当然这个只能防一下ps，如果是诚心的从原始sample上就作假，那就只能找个人重复了
on |
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S**********e
发帖数: 1789 | 46 造假还分诚心和意外吗？既然ps和从上样开始造假性质结果都一样，那聪明人一定会从
上样开始，因为这样最安全。所以，要想保证自己实验室结果正确，只能让自己实验室
的人互相验证，而且要在相互不知道结果的情况下验证，防止川帮。自己实验室如果都
不能重复，还指望别的实验室能重复吗？ |
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c****z
发帖数: 299 | 47 哈哈，是的是的，造假哪里还有意外。应该说造假比较粗糙和造假比较认真 LOL |
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c********6
发帖数: 189 | 48 ask your collaborator/friend in other lab/school/institute to repeat the key
results.
on |
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d********r
发帖数: 3279 | 49 it's about time!
http://www.nytimes.com/2013/02/20/science/new-3-million-prizes-
Eleven scientists, most of them American, were scheduled to be named on
Wednesday as the first winners of the world’s richest academic prize for
medicine and biology — $3 million each, more than twice the amount of the
Nobel Prize.
The award, the Breakthrough Prize in Life Sciences, was established by four
Internet titans led by Yuri Milner, a Russian entrepreneur and
philanthropist who caused a stir last summer whe... 阅读全帖 |
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r***e
发帖数: 2539 | 50 xenograft应该是工业界的人做的比较多。Bob Weinberg实验室出来的做乳腺癌比较多？
我不是很熟这一块。
另外你的药物是哪一类的，找相关的人比较好。做动物模型的人对某个药物不一定熟悉
。 |
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