b********n
发帖数: 38600 | 1 http://journal.frontiersin.org/article/10.3389/fpsyg.2014.00852
Introduction
Access to highly palatable and calorically rich foods is a major
contributing factor to the increasing rates of obesity worldwide (Caballero,
2007). Eating is essential for survival and is underpinned by the
fundamental physiological need to consume energy. However, our basic
requirements for nutrients and energy to maintain physiological homeostasis
are often exceeded by an abundant source of readily available and conv... 阅读全帖 |
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c*****e
发帖数: 94 | 2 Pedunculopontine tegmental nucleus of the rat: Cytoarchitecture,
cytochemistry, and some extrapyramidal connections of the mesopontine
tegmentum
1. David B. Rye,
2. Clifford B. Saper,
3. Henry J. Lee,
4. Dr. Bruce H. Wainer^*
Article first published online: 9 OCT 2004
Journal of Comparative Neurology
Please send to: r******[email protected]
Thanks a lot! |
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a**p
发帖数: 49 | 3 Neural bases for addictive properties of benzodiazepines p769
Benzodiazepines, such as valium, are used both in clinics and for
recreational purposes, but lead to addiction in some individuals. Addictive
drugs increase the levels of dopamine and trigger synaptic adaptations in
the mesolimbic reward system, but the neural basis for the addictive nature
of benzodiazepines remains elusive. Here, they are shown to increase firing
of dopamine neurons in the ventral tegmental area through GABAA recept |
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n***d
发帖数: 8857 | 4 你说的这个解释是现在很流行的解释吧,也正是我不明白的地方。我提到的这个实验里
老鼠根本没有接触食物，只是按一下开关就电击一下多他命分泌区ventral tegmental
area (VTA),老鼠不停的按就好像多他命也能产生快感一样。wiki里是这么说的，
Electrical stimulation of the VTA or its output pathways can itself serve as
a potent reward: animals will quickly learn to press a lever if it results
in stimulation of dopamine release, and often will continue pressing the
lever for a long time, at steadily increasing rates.wiki里也提到了你说的解释
，所以我觉得很矛盾。 |
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M***D
发帖数: 249 | 5 Is the patient a smoker? Hypertensive?
If so, he likely had a small pontine tegmental infarction.
Agree MRI the patient and 让糖姐赚一笔 :)) |
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n*******c
发帖数: 501 | 6 让糖姐姐赚的意思是明知MRI正常也要order，所以糖姐姐轻松发报告赚钱lol
to have a pontine tegmental infarct affecting CN vii only,without any gaze
palsy or abduction deficit is highly unlikely, if not impossible...
btw, if one can explain one-and-a-half syndrome clearly in the round, he
will impress most of the neurology attendings :) |
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