B**W 发帖数: 2273 | 1 Genes Play Major Role in Primate Social Behavior, Study Finds
By NICHOLAS WADE
Social behavior among primates — including humans — has a substantial
genetic basis, a team of scientists has concluded from a new survey of
social structure across the primate family tree.
The scientists, at the University of Oxford in England, looked at the
evolutionary family tree of 217 primate species whose social organization is
known. Their findings, published in the journal Nature, challenge some of
the leadin... 阅读全帖 |
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h*h 发帖数: 18873 | 2 Most mammals reach adulthood within months and die in their teens or 20s.
Not so with humans and other primates, which take years to become adults,
then live for decades and reproduce infrequently.
Now researchers are reporting that a reason for the disparity may lie in
metabolic rates. According to a new study in Proceedings of the National
Academy of Sciences, primates burn about half as many calories per day as
mammals of comparable size — and not simply because the other mammals are
more act... 阅读全帖 |
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s*****n 发帖数: 209 | 4 http://abcnews.go.com/Technology/story?id=7603618&page=1
Scientists say a 47-million-year-old fossil found in Germany may be a key
link to explain the evolution of modern human beings.
PHOTO Graphic Illustration Scientists say a 47-million-year-old fossil found
in Germany may be a key link to explain the evolution of modern human
beings.
The fossil, of a young female that probably resembled a modern-day lemur, is
described as "the most complete primate fossil ever found." It is small --
with a b |
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y**********g 发帖数: 2285 | 5 靠谱吗?
LONDON: Humans are actually hybrids, who emerged as an offspring of a male
pig and a female chimpanzee, according to one of the world's leading
geneticist.
Turning the theory of human ancestry on its head, Dr Eugene McCarthy — one
of the world's leading authorities on hybridization in animals from the
University of Georgia has suggested that humans didn't evolve from just apes
but was a backcross hybrid of a chimpanzee and pigs.
His hypothesis is based on the fact that though humans have ma... 阅读全帖 |
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g*********d 发帖数: 233 | 6 科学家呼吁关注全球基因组数据库污染
样品处理有可能是导致DNA数据库广泛污染的最主要原因
2月16日发表在《公共科学图书馆·综合》(PLoS ONE)期刊上的一份研究报告称康涅
狄格大学的遗
传学家Mark Longo及同事发现由顶级公共测序机构提供的测序结果构建的基因组数据库
中的大约
1/5的细菌、植物和非灵长类动物基因组数据受到了人类DNA的污染,样品处理有可能是
导致DNA数据
库广泛污染的最主要原因。这一研究报告引起了生物研究人员及各大权威媒体的高度关
注,《科学
家》(The Scientist)杂志以及《自然》(Nature)杂志均在其官方网络上第一时间
对这一事件
进行了报道。
Mark Longo等在报告中呼吁科学家们需更加努力以确保测序获得的基因组不受到污染,
并应对来自
公共基因组数据库的基因组进行潜在污染检测。
“基因组污染是一个大问题,但却不是一个新问题,”加州大学进化生物学家、美国能
源部联合基因组
研究所系统发育基因组学计划负责人Jonathan Eisen说:“这篇论文或可帮助提醒人们
注意这一问
题。”
污染有可能在测序的任何一个阶段导入到基因组序列中... 阅读全帖 |
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发帖数: 1 | 7 Sexually transmitted diseases reduce the willingness of female baboons to
mate
8 hours ago
The German Primate Center
Would you like to receive trending story notifications on your smartphone?
A female olive baboon at peak estrus rejects the mating attempt of a male.
Credit: Filipa Paciência
Sexually transmitted diseases are widespread among animals and humans.
Humans, however, know a multitude of protective and hygienic measures to
protect themselves from infection. An international research... 阅读全帖 |
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a***a 发帖数: 12425 | 8 【珍稀动物】萌萌大美瞳---超濒危的绒哆倭丛猴
前两天看到的一个关于世界二十五种最濒危的灵长动物的帖子,看到第一个猴子的图片
一下子就被吸引了。它有一对扇风耳,一双滚圆的眼睛,一只可爱的鼻子,一条长长的
刷子似的大尾巴,双手双脚紧紧地抓在一个树枝上面。这种猴子名叫Rondo Dwarf Gala
go (Galagoides Rondoensis),在网上查了一下,中文翻成了一个很拗口的名字:绒哆
倭丛猴。
绒哆倭丛猴是一种体重仅两盎司(六十克)的小型物种,属于灵长目原猴亚目,和狐猴
、懒猴、眼镜猴等萌物们亲缘关系不远。直到一九九六年人们才知道这类物种的存在,
并从那时起把它们视为丛猴种类中最小的一种。如今绒哆倭丛猴已经从濒危类变为极度
濒危类动物。
绒哆倭丛猴的大眼睛和大耳朵不单单是用来卖萌,主要是用于在夜间活动,吃昆虫和果
实,而白天它们就会搭一个窝在树上睡觉。绒哆倭丛猴居住在非洲大陆坦桑尼亚海岸的
一些旱生森林中,它们的家并不需要多大的地方。尽管有些这类森林是在国家公园的范
围内,然而,人类的开荒活动,不管是为了种田、还是获得木材和木炭,让它们的小小
家园变得支离破碎、狭窄不堪。... 阅读全帖 |
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l**********1 发帖数: 5204 | 9 female did 陈世美 behavior will be more genetic/evolutionary adaptation/
trade off/red queen dominated
if 博爱 concept ( Green Cap receiver totally will accept her/his competitor
’s offspring although kid is that competitor’s DNA).
pls refer
Opie C et al., (2013).
Male infanticide leads to social monogamy in primates.
Proc Natl Acad Sci U S A. 110: 13328-32.
Abstract
Although common in birds, social monogamy, or pair-living, is rare among
mammals because internal gestation and lactation in mammals ma... 阅读全帖 |
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s********n 发帖数: 4346 | 11 The real reasons people oppose gay marriage
So far, we've examined the reasons everyone give for opposing gay marriage.
Let's examine now the real reasons people oppose it, even fear it:
1. Just not comfortable with the idea. The fact the people aren't
comfortable with the idea stems primarily from the fact that for many years,
society has promoted the idea that a marriage between members of the same
sex is ludicrous, mainly because of the objections raised above. But if
those objections don't m... 阅读全帖 |
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s********n 发帖数: 4346 | 12 【 以下文字转载自 WaterWorld 讨论区 】
发信人: spinozafun (花脚猫), 信区: WaterWorld
标 题: The real reasons why people are against gay marriage
发信站: BBS 未名空间站 (Sat Jun 9 21:43:39 2012, 美东)
The real reasons people oppose gay marriage
So far, we've examined the reasons everyone give for opposing gay marriage.
Let's examine now the real reasons people oppose it, even fear it:
1. Just not comfortable with the idea. The fact the people aren't
comfortable with the idea stems primarily from the fact that for many years,
... 阅读全帖 |
|
l*****o 发帖数: 19653 | 13 这不是联想,而是某种科学假设,因为事实摆在眼前:
Men will be happy to know that humans have the largest primate penis with
respect to overall body size. Gorillas oddly enough have one of the smallest
primate penises, despite the fact that they are the largest primates on
Earth. Gorillas penis size averages around a paltry two inches. |
|
g*****5 发帖数: 91 | 14 【 以下文字转载自 pets 讨论区 】
发信人: benbenma (猪猪), 信区: pets
标 题: [合集] 如果你不愿意吃狗肉和猫肉,为什么吃鸡肉? (转载)
发信站: BBS 未名空间站 (Sat Nov 27 22:41:37 2010, 美东)
☆─────────────────────────────────────☆
purity (purity) 于 (Sat Nov 27 22:10:55 2010, 美东) 提到:
【 以下文字转载自 Vegetarianism 俱乐部 】
发信人: purity (purity), 信区: Vegetarianism
标 题: 如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
发信站: BBS 未名空间站 (Thu Nov 25 07:39:04 2010, 美东)
http://article.yeeyan.org/view/185743/147710
如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
moviemovie于2010-11-04 00:42:11翻译
作者:布鲁斯.弗莱德茨(Bruce Friedrich... 阅读全帖 |
|
p****y 发帖数: 23737 | 15 【 以下文字转载自 Vegetarianism 俱乐部 】
发信人: purity (purity), 信区: Vegetarianism
标 题: 如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
发信站: BBS 未名空间站 (Thu Nov 25 07:39:04 2010, 美东)
http://article.yeeyan.org/view/185743/147710
如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
moviemovie于2010-11-04 00:42:11翻译
作者:布鲁斯.弗莱德茨(Bruce Friedrich)
最近数以亿计的鸡蛋被召回,对于经常食用鸡蛋的大众来说,这无疑是个坏消息。令人
没有想到的是,这样一来,鸡被推到了聚光灯下,全社会都在关注这些鸡肉的来源。
由此产生的的后果就是漫天铺地的媒体报道。无论是黛安.索亚,还是艾米.古德曼的
电视报道(译者注:这两位都是著名的电视记者),无论是纽约时报数篇评论还是CNN的
简.米歇尔深度分析都让美国民众震惊,他们没有料到鸡在美国受到如此残忍的对待。
因祸得福的是美国人因此认识到了鸡的遭遇。在美国的任何地方,数以百万... 阅读全帖 |
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O*******d 发帖数: 20343 | 16 Men will be happy to know that humans have the largest primate penis with
respect to overall body size. Gorillas oddly enough have one of the smallest
primate penises, despite the fact that they are the largest primates on
Earth. Gorillas penis size averages around a paltry two inches. Chimpanzees
are much smaller than gorillas, yet sport a penis twice as long.
http://voices.yahoo.com/penis-size-animal-kingdom-272333.html?c |
|
p****y 发帖数: 23737 | 17 【 以下文字转载自 Vegetarianism 俱乐部 】
发信人: purity (purity), 信区: Vegetarianism
标 题: 如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
发信站: BBS 未名空间站 (Thu Nov 25 07:39:04 2010, 美东)
http://article.yeeyan.org/view/185743/147710
如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
moviemovie于2010-11-04 00:42:11翻译
作者:布鲁斯.弗莱德茨(Bruce Friedrich)
最近数以亿计的鸡蛋被召回,对于经常食用鸡蛋的大众来说,这无疑是个坏消息。令人
没有想到的是,这样一来,鸡被推到了聚光灯下,全社会都在关注这些鸡肉的来源。
由此产生的的后果就是漫天铺地的媒体报道。无论是黛安.索亚,还是艾米.古德曼的
电视报道(译者注:这两位都是著名的电视记者),无论是纽约时报数篇评论还是CNN的
简.米歇尔深度分析都让美国民众震惊,他们没有料到鸡在美国受到如此残忍的对待。
因祸得福的是美国人因此认识到了鸡的遭遇。在美国的任何地方,数以百万... 阅读全帖 |
|
b******a 发帖数: 12216 | 18 ☆─────────────────────────────────────☆
purity (purity) 于 (Sat Nov 27 22:10:55 2010, 美东) 提到:
【 以下文字转载自 Vegetarianism 俱乐部 】
发信人: purity (purity), 信区: Vegetarianism
标 题: 如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
发信站: BBS 未名空间站 (Thu Nov 25 07:39:04 2010, 美东)
http://article.yeeyan.org/view/185743/147710
如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
moviemovie于2010-11-04 00:42:11翻译
作者:布鲁斯.弗莱德茨(Bruce Friedrich)
最近数以亿计的鸡蛋被召回,对于经常食用鸡蛋的大众来说,这无疑是个坏消息。令人
没有想到的是,这样一来,鸡被推到了聚光灯下,全社会都在关注这些鸡肉的来源。
由此产生的的后果就是漫天铺地的媒体报道。无论是黛安.索亚,还是艾米.古德曼的
电视报道(译者注:这两位都是著... 阅读全帖 |
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a*********7 发帖数: 30080 | 19 MMP: Most Marked Primate
MWP: Most Watering Pumper
MVB: Moisture Vapor Barrier
MCP: Most Consumed Protein
MVP: Most Viewed Primate
MLP: Most Loved Primate |
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p****y 发帖数: 23737 | 20 http://article.yeeyan.org/view/185743/147710
如果你不愿意吃狗肉和猫肉,为什么吃鸡肉?
moviemovie于2010-11-04 00:42:11翻译
作者:布鲁斯.弗莱德茨(Bruce Friedrich)
最近数以亿计的鸡蛋被召回,对于经常食用鸡蛋的大众来说,这无疑是个坏消息。令人
没有想到的是,这样一来,鸡被推到了聚光灯下,全社会都在关注这些鸡肉的来源。
由此产生的的后果就是漫天铺地的媒体报道。无论是黛安.索亚,还是艾米.古德曼的
电视报道(译者注:这两位都是著名的电视记者),无论是纽约时报数篇评论还是CNN的
简.米歇尔深度分析都让美国民众震惊,他们没有料到鸡在美国受到如此残忍的对待。
因祸得福的是美国人因此认识到了鸡的遭遇。在美国的任何地方,数以百万计的鸡被关
在十分拥挤的笼子里,拥挤得无法展开翅膀或者呼吸到新鲜空气。它们的一生就这样度
过,直至死去。每一只鸡蛋都代表着34小时难以化解的痛楚。美国每年消耗九亿只鸡,
消耗量相当于牛的两百倍,猪的一百倍。还没有计算其中有人终止吃红肉,改为吃鸡肉
。这样算下来,实际被吃掉的鸡肉和鸡蛋的... 阅读全帖 |
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O*******d 发帖数: 20343 | 21 你显然是生物外行,科盲。难怪那么幼稚。 要攻击进化论,先把进化论的理论搞清楚
了再发言。
1. Archidiacono, N., Storlazzi, C.T., Spalluto, C., Ricco, A.S., Marzella
, R., Rocchi, M. 1998. ‘Evolution of chromosome Y in primates.’ Chromosoma
107:241-246.
2. Britten, R.J. 2002. ‘Divergence between samples of chimpanzee and
human DNA sequences is 5% counting indels.’ Proceedings National Academy
Science 99:13633-13635.
3. Fujiyama, A., Watanabe, H., Toyoda, A., Taylor, T.D., Itoh, T., Tsai,
S.F., Park, H.S., Yaspo, M.L., Lehrach, H., C... 阅读全帖 |
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g*******y 发帖数: 202 | 22 在缅甸发现化石
Researchers agree that our immediate ancestors, the upright walking apes,
arose in Africa. But the discovery of a new primate that lived about 37
million years ago in the ancient swamplands of Myanmar bolsters the idea
that the deep primate family tree that gave rise to humans is rooted in Asia
. If true, the discovery suggests that the ancestors of all monkeys, apes,
and humans—known as the anthropoids—arose in Asia and made the arduous
journey to the island continent of Africa almost 4... 阅读全帖 |
|
|
s******n 发帖数: 518 | 24 【 以下文字转载自 History 讨论区 】
发信人: shaodian (有熊), 信区: History
标 题: 美国生物实验室泄露
发信站: BBS 未名空间站 (Sun Mar 22 15:25:05 2020, 美东)
Google翻译一次只能3900字符。
https://www.usatoday.com/story/news/2015/05/28/biolabs-pathogens-location-
incidents/26587505/
Investigation reveals hundreds of accidents, safety violations and near
misses put people at risk
Alison Young and Nick Penzenstadler, USA TODAY
Vials of bioterror bacteria have gone missing. Lab mice infected with deadly
viruses have escaped, and wild rodents have b... 阅读全帖 |
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B**W 发帖数: 2273 | 25 The National Institutes of Health on Thursday suspended all new grants for
biomedical and behavioral research on chimpanzees and accepted the first
uniform criteria for assessing the necessity of such research. Those
guidelines require that the research be necessary for human health, and that
there be no other way to accomplish it.
In making the announcement, Dr. Francis S. Collins, the director of the N.I.
H., said that chimps, as the closest human relatives, deserve “special
consideration and ... 阅读全帖 |
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H**U 发帖数: 1814 | 26 给索男们增强点信心,别像某些人被美国文化洗脑后自恨得要把自己族裔都杀光了不可。
http://en.wikipedia.org/wiki/Neoteny
http://erectuswalksamongst.us/Chap6.html
A few key points:
1.“Neoteny” (new-stretch) refers to a gene-controlled change in the way
individuals mature, where they mature sexually at about a normal rate but,
although the body grows in size as they become sexually mature, their
juvenile features (and their ancestors’ juvenile features) are retained
into adulthood and are not replaced by distinctively different adult
featur... 阅读全帖 |
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l******r 发帖数: 76 | 27 Dear all:
I have 23 paper, 11 first author, add two conference abstract, 4 chinese
book chapter.
Total independent citation 60.
Have some local newspaper and TV report
As first author, discovered two new primate species.
As co-author, named 14 new primate species.
no review experience, try to get some but slow.
no award.
Do you think my case is good for Eb1b?
Thank you very much,
Peter |
|
c**i 发帖数: 6973 | 28 【 以下文字转载自 Sex 讨论区 】
发信人: choi (choi), 信区: Sex
标 题: Re: 我bf在做之前喜欢打我的pp
发信站: BBS 未名空间站 (Sun Jun 22 15:04:12 2008)
I am a male biologist.
Hmm. your situation reminds me of female primates (except humans). See, for
example, Domb LG and Pagel M, Sexual swellings advertise female quality in
wild baboons. Nature, volume 410, pages 204-206 (8 March 2001)
("The females of many Old World primate species produce prominent and
conspicuous swellings of the perineal skin around the time of ovulation.")
The l |
|
b*s 发帖数: 82482 | 29 aye-aye:
The aye-aye (Daubentonia madagascariensis) is a lemur, a strepsirrhine
primate native to Madagascar that combines rodent-like teeth and a special
thin middle finger to fill the same ecological niche as a woodpecker. It is
the world's largest nocturnal primate, and is characterized by its unusual
method of finding food; it taps on trees to find grubs, then gnaws holes in
the wood and inserts its narrow middle finger to pull the grubs out. The
only other animal species known to find food ... 阅读全帖 |
|
m******e 发帖数: 536 | 30 【 以下文字转载自 Animals 讨论区 】
发信人: meditate (meditate), 信区: Animals
标 题: 老猩猩作画赢得艺术比赛第一名获一万美元奖励
发信站: BBS 未名空间站 (Fri Aug 30 13:30:29 2013, 美东)
一只37岁退休的路易斯安那州实验室老猩猩,用它的舌头沾染颜料所作的画,赢得全美
猩猩艺术比赛第一名获一万美元奖励。
真心觉得这个老猩猩的画有意思,如果不知道是猩猩舌头沾染画的,你说这是什么现代
抽象派艺术大师的画,我也信了。
JANET McCONNAUGHEY16 hours ago
.
NEW ORLEANS (AP) — A painting by a 37-year-old Louisiana primate who
applies color with his tongue instead of a brush has been deemed the finest
chimpanzee art in the land.
Brent, a retired laboratory animal, was the t... 阅读全帖 |
|
m******e 发帖数: 536 | 31 【 以下文字转载自 Animals 讨论区 】
发信人: meditate (meditate), 信区: Animals
标 题: 老猩猩作画赢得艺术比赛第一名获一万美元奖励
发信站: BBS 未名空间站 (Fri Aug 30 13:30:29 2013, 美东)
一只37岁退休的路易斯安那州实验室老猩猩,用它的舌头沾染颜料所作的画,赢得全美
猩猩艺术比赛第一名获一万美元奖励。
真心觉得这个老猩猩的画有意思,如果不知道是猩猩舌头沾染画的,你说这是什么现代
抽象派艺术大师的画,我也信了。
JANET McCONNAUGHEY16 hours ago
.
NEW ORLEANS (AP) — A painting by a 37-year-old Louisiana primate who
applies color with his tongue instead of a brush has been deemed the finest
chimpanzee art in the land.
Brent, a retired laboratory animal, was the t... 阅读全帖 |
|
S*******n 发帖数: 12762 | 32 OK, ladies and gentlemen, let me try something new here.
Chapter 1, The Mermaid
I was stunned.
Miles of white beach, shinning under gentle, silver moonlights, was overstre
tching its beauty silently in the dimness, moaning rhythmically as waves pun
ched the shores, just like, well, just like a naked lady twisting her body f
orcefully yet gracefully in the darkness, longing to be touched.
I was alone. Not a single living soul on the beach. It was my domain. "You n
eed to get naked," a voice in my... 阅读全帖 |
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b*********d 发帖数: 596 | 33 http://www.npr.org/2011/08/09/138957812/evangelicals-question-t
Let's go back to the beginning — all the way to Adam and Eve, and to the
question: Did they exist, and did all of humanity descend from that single
pair?
According to the Bible (Genesis 2:7), this is how humanity began: "The Lord
God formed man of the dust of the ground, and breathed into his nostrils the
breath of life; and man became a living soul." God then called the man Adam
, and later created Eve from Adam's rib.
Polls by Gal... 阅读全帖 |
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S**U 发帖数: 7025 | 34 尼采说过失去盲目的信仰之后,如何挣扎找到自己相信的美好。
Nietzsche's "Three Metamorphoses"
by Jason Francois
In the section of Thus Spoke Zarathustra entitled, "Of the Three
Metamorphoses,” Zarathustra describes a process of human transformation.
This transformation will become Zarathustra's answer to the fears and
anxieties created by the "death of God".
Nietzsche begins: "I name you three metamorphoses of the spirit: how the
spirit shall become a camel, and the camel a lion, and the lion at last a
child".
These metaphors... 阅读全帖 |
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w********1 发帖数: 3492 | 35 Tue, 12 Jun 2012 12:47:53 PDT
With the first Mid-2012 MacBook Pro and MacBook Air models reaching the
public, Primate Labs has collated some data from its Geekbench 2
benchmarking database to assess the raw performance of these systems
compared to their predecessors.
For the MacBook Pro, Primate Labs has data on four different models: the new
Retina model with 2.3 GHz and 2.6 GHz processors and the non-Retina model
with 2.3 GHz and 2.7 GHz processors. The top-of-the-line 2.7 GHz system
register... 阅读全帖 |
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w********1 发帖数: 3492 | 36 Wed, 13 Jun 2012 13:29:20 PDT
Back in mid-May, a pair of Geekbench 2 benchmarks that claimed to be from
unreleased MacBook Pro and iMac models appeared, setting off speculation
that updates to both lines might be imminent if the entries were indeed
legitimate. But with Apple not updating the iMac earlier this week at its
Worldwide Developers Conference keynote, those looking for an upgraded all-
in-one desktop Mac have been left waiting.
With updated MacBook Pro models reaching the public, Prim... 阅读全帖 |
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w********1 发帖数: 3492 | 37 Mon, 18 Jun 2012 07:59:43 PDT
Last week, Primate Labs summarized its Geekbench 2 database results for
Apple's new MacBook Air and 15-inch MacBook Pro models, but did not address
the 13-inch MacBook Pro as not enough data had been collected at that time.
But over the past week more data has come in, and the firm now shares its
results which show the new 13-inch models are yielding approximately 10-15%
higher Geekbench 2 scores than both the corresponding previous-generation 13
-inch MacBook Pro m... 阅读全帖 |
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l**d 发帖数: 472 | 38 According to one hypothesis, human being is kept in juvenile status compared
to the ancestor species. Lack of body hair compared to other primate is
regarded as supporting evidence for this hypothesis because other primates
do not have much body hair in early development stage. |
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e*******o 发帖数: 4654 | 39 不同类群的 primate,群内数量均值有差别(Primate ecology and social
organization 手头一本书里有这篇,就顺便看了下)。种群的数量变化是肯定的。但
是像你说的那么magic, 没听说过。不是专搞这个的,不清楚调节机制。
有些虫子是 aggregation pheromones 调控的,少的时候,能吸引更多加入,多了,会
释放 inhibit pheromones. |
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m******g 发帖数: 467 | 41 PNAS 14.1.28
稍微了解一下:
1. Searching for missing heritability: Designing rare variant association
studies
2. Transcriptional occlusion caused by overlapping promoters
小知识:
1. Deletion of conserved protein phosphatases reverses defects associated
with mitochondrial DNA damage in Saccharomyces cerevisiae
2. Estrogen receptor α polymorphism in a species with alternative
behavioral phenotypes
3. Evolutionary genetics and implications of small size and twinning in
callitrichine primates
4. In vitro sel... 阅读全帖 |
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s*****c 发帖数: 182 | 42 看起来还行吧
ARC-520 Phase 2a Study Update
Completed dosing of 1 mg/kg and 2 mg/kg dose cohorts
Initial blinded data suggest that the magnitude of HBsAg knockdown is
similar to non-human primate studies, including the chronically infected
chimpanzee reported on previously
Duration of knockdown appears to be substantially more sustained than in non
-human primates, with patients in the 2 mg/kg group still demonstrating
substantial knockdown after 8 weeks, which is the most recent time point
available
H... 阅读全帖 |
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s*****c 发帖数: 182 | 43 看起来还行吧
ARC-520 Phase 2a Study Update
Completed dosing of 1 mg/kg and 2 mg/kg dose cohorts
Initial blinded data suggest that the magnitude of HBsAg knockdown is
similar to non-human primate studies, including the chronically infected
chimpanzee reported on previously
Duration of knockdown appears to be substantially more sustained than in non
-human primates, with patients in the 2 mg/kg group still demonstrating
substantial knockdown after 8 weeks, which is the most recent time point
available
H... 阅读全帖 |
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l*********i 发帖数: 332 | 44 多谢哥们点评。
扪心自问,去年的Dev Cell的工作在分子水平上我还是非常满意,后来adrian bird,
narry kim都在nature review里面专门放在figure里面点评了。
这个转基因猴子的工作历时漫长,本来就是09-10年赶鸭子上架,那时候年青人无知无
畏,到猴子11年出来以后势成骑虎,我一个做分子的硬起头皮做起各种猴子的行为学分
析,幸好有个硕士技术员听话,一般学生无法干这种无法预测啥时候能出文章的课题,
做了两年好像有点意思,投稿又历经波折,最后呢,其实并不是了不起的科学发现,只
是第一次把human autism gene转到猴子里面,确实有很强的autism phenotypes, 以至
于到第二代居然还具有autism-like phenotypes,所以以后为做autism brain imaging
提供了一个primate的model, 可以知道究竟autism gene-brain imaging的直接联系。
如果非要说一点意义,就这些吧。
我个人的兴趣并非是灵长类的神经生物学,不是做primate neurobiology的,我也不打
算改... 阅读全帖 |
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h*****b 发帖数: 492 | 45 Penis bone lost through evolution
Nature 540, 486 (22 December 2016) doi:10.1038/540486b
Our monogamous lifestyle may explain why humans, unlike many other mammals,
lack a penis bone.
The bone, called a baculum, rests at the end of the penis and is thought to
provide structural support and prolong copulation. Matilda Brindle and
Christopher Opie at University College London analysed the size of bacula in
nearly 2,000 species of mammal, including primates and carnivores. They
found that species t... 阅读全帖 |
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l****z 发帖数: 29846 | 46 【 以下文字转载自 Biology 讨论区 】
发信人: shendoc (shendoc), 信区: Biology
标 题: Re: arc-520: 治愈乙肝的新药?
发信站: BBS 未名空间站 (Tue Aug 12 16:27:04 2014, 美东)
看起来还行吧
ARC-520 Phase 2a Study Update
Completed dosing of 1 mg/kg and 2 mg/kg dose cohorts
Initial blinded data suggest that the magnitude of HBsAg knockdown is
similar to non-human primate studies, including the chronically infected
chimpanzee reported on previously
Duration of knockdown appears to be substantially more sustained than in non
-human primates, with ... 阅读全帖 |
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f**d 发帖数: 768 | 47 这是一本计算神经科学的优秀著作,全文拷贝这里(图和公式缺),有兴趣的同学可以
阅读
如需要,我可以分享PDF文件(--仅供个人学习,无商业用途)
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖 |
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m******e 发帖数: 536 | 48 一只37岁退休的路易斯安那州实验室老猩猩,用它的舌头沾染颜料所作的画,赢得全美
猩猩艺术比赛第一名获一万美元奖励。
真心觉得这个老猩猩的画有意思,如果不知道是猩猩舌头沾染画的,你说这是什么现代
抽象派艺术大师的画,我也信了。
JANET McCONNAUGHEY16 hours ago
.
NEW ORLEANS (AP) — A painting by a 37-year-old Louisiana primate who
applies color with his tongue instead of a brush has been deemed the finest
chimpanzee art in the land.
Brent, a retired laboratory animal, was the top vote-getter in an online
chimp art contest organized by the Humane Society of the United States,
which announced the results Thursday... 阅读全帖 |
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p*********w 发帖数: 23432 | 49 中英文艾未未微博选登(2009.6~2010.7)
Ai Weiwei( @aiww )Tweet Quotes 1 (June 2009—July 2010)
1. 孩子们肾结石、大头娃娃、被拐卖、被活埋、被开苞、被毒害,但是要让他们保持
纯洁。
1. It does not matter children suffer from kidney stones or abnormally big
heads, and it does not matter children have been abducted, buried alive,
poisoned or lost their virginity, what matters is they remain mentally pure.
June 10, 2009 12:30:31
2. 我郑重的宣布,一个开骂的时代开始了,我们要轻声的骂死敌人。
2. I solemnly declare that here comes a name-calling era, and we would curse
the enemy softly ... 阅读全帖 |
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