l**********1
发帖数: 5204 | 4 sure Hsp90N
LZ
pls refer one review:
PMID 19179103
by Li Y et al. (2009).
Drug Resist Updat. 12: 17-27.
its pp22 right column bottom:
>Another cytoplasmic variant in mammals, Hsp90N, completely lacks the N-
terminal ATPase
domain and appears to be membrane associated (Grammatikakis et al., 2002).
Higher
eukaryotes possess a distinct endoplasmic-reticulum isoform, Grp94 (Ni and
Lee, 2007) and
a mitochondrial isoform, Trap1 (Felts et al., 2000). Neither clientele nor
the biological role of
these i... 阅读全帖 |
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