y***v 发帖数: 270 | 1 你们看看: 比较长,
转一篇文章。让事实为肖传国说话
转自:虹桥科教论坛 http://www.rainbowplan.org/bbs/topic.php?topic=114563&select=&forum=1
有人在散仙谷转了一篇文章。应该把这篇文章广为转发。让当局和国内不明真相的人民
都知道肖传国的医学探索的价值。方舟子夹私打假必然会被钉在科学的耻辱柱上。
“肖氏反射弧”真相解析
肖传国教授在世界上第一个提出并证实 “人工建立体神经-内脏神经反射弧” 用于治
疗各种脊髓损伤导致的排尿障碍。这一发现在肖传国与方舟子之间挑起了一场科学与反
科学长达五年的论战。为帮助公众了解这场论战的事实真相,本文首先从学术角度根据
科学文献和科学事实对“肖氏反射弧”作一番解析。
反射是神经支配机体生理机能的基本方式。反射弧一般由感受器,传入神经,反射中枢
,传出神经和效应器组成。正常的排尿反射由位于脑干和大脑皮层的高级排尿中枢控制
达骶髓的排尿反射初级中枢完成。膀胱充盈时,膀胱壁的牵张感受器受到刺激而兴奋。
冲动传入高级中枢产生排尿欲。中枢经过判断认为可以排尿,于是发出神经冲动沿下行
传导束到脊髓初... 阅读全帖 |
|
Z**S 发帖数: 1211 | 2 Outcomes of Lumbar to Sacral Nerve Rerouting for Spina Bifida
The Journal of Urology. Volume 184, Issue 2 , Pages 702-708, August 2010
Purpose
Restoring bladder and bowel function in spina bifida by creation of a skin-
central nervous system-bladder reflex arc via lumbar to sacral nerve
rerouting has a reported success rate of 87% in China. We report 1-year
results of the first North American trial on nerve rerouting.
Materials and Methods
Nine subjects were enrolled in the study. Intradural lum... 阅读全帖 |
|
e****0 发帖数: 678 | 3 • Exaggerated deep tendon reflexes can be seen in lock in syndrome.
• Non bleeding varices are managed with nonselective beta-
adrenergic antagonists, such as propranolol.
• Sclerotherapy, endoscopic band ligation, and surgery are
indicated after a patient has a first episode of variceal bleeding.
• TIPS is a last resort in variceal bleeding unresponsive to
medical and endoscopic intervention.
• Ischemic colitis
CT—thickening of eth bowel ... 阅读全帖 |
|
x*****9 发帖数: 48 | 4 TWO-YEAR OUTCOMES WITH LUMBAR TO SACRAL NERVE
REROUTING IN SPINA BIFIDA
Kevin Feber*, Damon Dyche, Benjamin Girdler, Cindy Turzewski,
Gary Trock, William Nantau, Evan Kass, Kenneth Peters, Royal
Oak, MI
INTRODUCTION AND OBJECTIVES: Restoring bladder and
bowel function in spina bifida by the creation of a skin-CNS-bladder
reflex arc via lumbar to sacral nerve rerouting has a reported success
rate of 87% in China. The purpose of this abstract is to report the 2 year
analysis of the first North Ame... 阅读全帖 |
|
|
y****i 发帖数: 2108 | 6 2011年1月的commentary review.
把结论部分给你摘出来:
The important message 。。。 is that the functional results 。。。are
less
favorable 。。。compared with the excellent reports of Xiao [1].
only one of eight sacral nerves innervating the bladder with at best
20–30%
of the total sacral parasympathetic outflow to the urinary bladder is
activated on stimulation for initiation of micturition.
The authors’ plea is noteworthy, to continue scientific evaluation of
the
risks and the benefits of this procedure before it may... 阅读全帖 |
|
l*****o 发帖数: 19235 | 7 随便找了个作者提供的链接看了一下。能看懂点英文的人,应该都知道作者在干吗了。
原文:
直到2010年8月在《泌尿学杂志》正式发表的其初步结果论文中,他们才承认9例脊
柱裂一年后“无一能完全自主控尿(Nopatient achieved complete
urinarycontinence)”。该结果遭到同行专家严厉批评和质疑。
原始链接:
http://www.ncbi.nlm.nih.gov/pubmed/20639040
RESULTS:
At 1 year 7 patients (78%) had a reproducible increase in bladder pressure
with stimulation of the dermatome. Two patients were able to stop
catheterization and all safely stopped antimuscarinics. No patient achieved
complete urinary continence. The majority of subjects repor... 阅读全帖 |
|
|
S******Q 发帖数: 475 | 9 You may want to read it again?
At 1 year 7 patients (78%) had a reproducible increase in bladder pressure
with stimulation of the dermatome. Two patients were able to stop
catheterization and all safely stopped antimuscarinics. No patient achieved
complete urinary continence. The majority of subjects reported improved
bowel function. One patient was continent of stool at baseline and 4 were
continent at 1 year. Of the patients 89% had variable weakness of lower
extremity muscle group at 1 month.... 阅读全帖 |
|
S******Q 发帖数: 475 | 10 "肖传国在平顶山煤矿作了14例, 随访13例, PETERS在
Beaumont作了11例, 随访9例. 肖传国的结果是11例有效 (85%, 11/13), PETERS的结果
是7例有效 (78%, 7/9). 争论7/9没有11/13高有什么意义? 任何生物学试验都会有误差
, 有效率会有高有底. 结果完全一样才是有问题."
争论7/9没有11/13高有什么意义? 争论这个当然没有意义.把这两个放在一起都没有任
何意义.不过是某些研究者MANIPULATE数据的小把戏.
平顶山的确11/13是指
关于手术后果CG XIAO 自己是这么说的
http://sci.rutgers.edu/forum/showthread.php?t=133933
3, What means 80% effective rate:
The effective rate included cured and improved, Cured means cath free,
infection free, no need for anticholineric (detropen)and residual ... 阅读全帖 |
|
w*l 发帖数: 2550 | 11 你有什么证据表明方舟子在“本着新闻的真实性原则在实地调查”?须知方舟子和肖传
国有旧仇,也有interest conflict,就是要调查,是不是也应该有third party组织进
行?
其二,方舟子有进行这项工作所必需的知识技能么?须知调查研究也是做学问。怎么设
计,组织,抽样,都是学问。你以为方舟子的调查结果表格是有相关学问的样子吗?还
有,你前面帖子还提过“正常的话”,要有主治医师观察,这里有吗?再有,1500人的
群体选了74人,怎么选的?什么标准?有代表性吗?这诸多问题不清楚,结果的可信度
从何而来?
其三,把那个医院的人全去掉,还有十几人,包括我举出的多个名校有title的教授,
你说他们每个人都有interest conflict?
其四,治愈率是个什么意思?那是偷换概念。100%治愈,那可能吗?有明显促进作用已
经是很可观了。
其五,你不熟悉这方面,我也不熟悉。但是可以看一看EUROPEAN UROLOGY 5 9 ( 2 01
1 ) 1 6 8 – 1 7 5对肖实验的评价。下面是一个pdf的链接,我贴了其中的Expert's
summary部分。应该很清楚,该方... 阅读全帖 |
|
c******n 发帖数: 5697 | 12 方呆子显然对医学一窍不通,没工作被逼上梁山靠打假赚饭吃,这次的确打错了人。这
种手术实验人数都不可能多,能有一点效果就很了不起了,这种数据在美国就可以申请
医疗保险付费了。 JofUrology也已经肯定手术是有效的:At 1 year 7 patients (78%
) had a reproducible increase in bladder pressure with stimulation of the
dermatome. Two patients were able to stop catheterization and all safely
stopped antimuscarinics. No patient achieved complete urinary continence.
The majority of subjects reported improved bowel function. One patient was
continent of stool at baseline and 4 were continent at 1 year. Of the |
|
p********k 发帖数: 97 | 13 7/9 is not even close to 85%. They mean different things.
what Xiao claimed is 85% of homeruns (i.e., complete urinary continence).
7/9 is just increase in bladder pressure with stimulation of the dermatome.
And even this could be due to "not voiding volitionally or using the newly
developed cutaneous reflex" as one commenter pointed out.
Go back and read the paper and the comments again. |
|
|
n*********0 发帖数: 1543 | 15 病毒延神经末梢进入皮节(Dermatome,一个神经末梢控制的一小片皮肤),扩散进周围组织细胞,引起感染,炎症,水疱。
分布规律就是神经分布的pattern.没有什么神奇的。
因为经络是古人对神经系统的模糊认识,所以中医看着就是沿着经络走的。 |
|
t******n 发帖数: 2939 | 16 ☆─────────────────────────────────────☆
junlver (junlver) 于 h 提到:
你去美国书店,不可否认的一点是,医药书架上基本都会有一栏放着非传统治疗书
籍。其中有很多是介绍关于中草药的功能和使用。很多不是照搬照抄的中医古籍翻译本
,是经过加工整理的。看看美国人对中医的态度,那是相当认真的。
西医有个最大的优点就是不管什么,只要有疗效,那就是好的,就是科学的。就是
不科学,那我也要拿出科学的统计数据,让他科学化。不知反对中医的人知道
Echinacea不?这个Echinacea中文名叫紫锥菊,虽然包含china但和中国没啥关系。这
可是欧美很常见的一种花。你家邻居家可能就种了!主要功能不用我说,自己查。我想
说的是,欧美人一样用草药。知道Astragalus么?对的,是黄芪。欧美人很喜欢用这两
个药混在一起用于对抗病毒感冒。中国的烂树根和鲜花可以治感冒!欧美也有秘方治感
冒。别以为感冒只能喝水,那是医生敷衍你。虽然很多疾病可以自愈,但是谁不希望症
状尽快减轻和治愈?要不然西医也没必要研发感冒药了。
中... 阅读全帖 |
|
D*******a 发帖数: 1723 | 17 不明白你为什么撒谎呢,明明是"89% had variable weakness of lower extremity
muscle group at 1 month.:翻译成中文是"第一个月时有不同程度的下肢肌无力"
到了你嘴里,居然成了"下肢瘫痪"
At 1 year 7 patients (78%) had a reproducible increase in bladder pressure
with stimulation of the dermatome. Two patients were able to stop
catheterization and all safely stopped antimuscarinics. No patient achieved
complete urinary continence. The majority of subjects reported improved
bowel function. One patient was continent of stool at baseline and 4 were
continent ... 阅读全帖 |
|
y***v 发帖数: 270 | 18 这是方的质疑文:
美国《泌尿学杂志》质疑“肖氏手术”
(2010-08-10 05:27:23)
美国《泌尿学杂志》最近登了“肖氏手术”在美国首批9个病人试验的结果,同时
刊登了两篇负面的编辑评论。特别指出该结果与肖传国所说的在中国的成功结果不符,
缺乏对照组,结果无统计学意义、自相矛盾,某些病人出现的改善可能是别的原因引起
的,该手术应该只用于探索性研究,如果迅速用于临床会有巨大的危险。
THE JOURNAL OF UROLOGY, Vol. 184, 702-708, August 2010
EDITORIAL COMMENTS
The authors present the first North American experience with lumbar to
sacral nerve rerouting for patients with spina bifida. The results from this
study and previous animal and clinical studies by Xiao clearly demonstrate
that n... 阅读全帖 |
|
w**a 发帖数: 4743 | 19 这位号称学生物的,解释一下这句话什么意思?
Although seven of nine patients were able to increase bladder pressure by
cutaneous stimulation of the respective lumbar dermatome, only two patients
were able to stop catheterization and no patient achieved complete urinary
continence. |
|
w**a 发帖数: 4743 | 20 这位号称学生物的,解释一下这句话什么意思?
Although seven of nine patients were able to increase bladder pressure by
cutaneous stimulation of the respective lumbar dermatome, only two patients
were able to stop catheterization and no patient achieved complete urinary
continence. |
|
w**a 发帖数: 4743 | 21 拿生物科班出身来吓人的伎俩太old了。
你翻译下这段文字的意思,看看你英文是否及格吧
Although seven of nine patients were able to increase bladder pressure by
cutaneous stimulation of the respective lumbar dermatome, only two patients
were able to stop catheterization and no patient achieved complete urinary
continence. |
|
W**H 发帖数: 716 | 22 这个“能自主大小便”的描述跟Peters的结果还是一致的:
“One year postoperatively, seven of
nine patients were able to generate at least a 10-cm H20 rise
in detrusor pressure with cutaneous stimulation of the
dermatome. Mean postvoid residual was 119 mL (range,
10–380 mL), with a maximum flow rate of 10 mL/s (range,
4–25 mL/s).”
http://www.springerlink.com/content/t26145l041079l56/
我觉的,说85%治愈或者完全解决大小便肯定是扯了。但是85%自主大小便这个恐怕还是
靠谱的。 |
|
W**H 发帖数: 716 | 23 我全部拷贝过来了,他们做了两次,第一次两个病人,6个月以后,反射弧都成功了,
15个月以后,停了药和导尿管。没有并发症。第二次,9个病人,一年以后,7个病人能
通过皮肤刺激导尿,但是没有一个能完全控尿,两个病人能下导尿管。其他两个手术带
来的好处一是肠功能,二是膀胱sensation。另,这9个病人中有一个 产生了垂足的后
果。除此外,没有其他的并发症发生。
从这些数据,可以看出,
1,反射弧形成的比例相当高,第一次,2/2, 第二次, 7/9 能自主小便。
2, 不能完全改善: 第一次,2/2停了药和导尿管;第二次,0/9可以完全自主导尿,2/9下了导尿管。
3, 其他好处: 肠功能,膀胱sensation
4, 并发症,或副作用,第一次, 0/2, 第二次: 1/9 垂足。
North American Studies
There have been attempts to replicate the Xiao procedure in
the United States. The first trial involved two traumatic SCI
patients—a ... 阅读全帖 |
|
w**a 发帖数: 4743 | 24 拿生物科班出身来吓人的伎俩太old了。
你翻译下这段文字的意思,看看你英文是否及格吧
Although seven of nine patients were able to increase bladder pressure by
cutaneous stimulation of the respective lumbar dermatome, only two patients
were able to stop catheterization and no patient achieved complete urinary
continence. |
|
W**H 发帖数: 716 | 25 这个“能自主大小便”的描述跟Peters的结果还是一致的:
“One year postoperatively, seven of
nine patients were able to generate at least a 10-cm H20 rise
in detrusor pressure with cutaneous stimulation of the
dermatome. Mean postvoid residual was 119 mL (range,
10–380 mL), with a maximum flow rate of 10 mL/s (range,
4–25 mL/s).”
http://www.springerlink.com/content/t26145l041079l56/
我觉的,说85%治愈或者完全解决大小便肯定是扯了。但是85%自主大小便这个恐怕还是
靠谱的。 |
|
W**H 发帖数: 716 | 26 我全部拷贝过来了,他们做了两次,第一次两个病人,6个月以后,反射弧都成功了,
15个月以后,停了药和导尿管。没有并发症。第二次,9个病人,一年以后,7个病人能
通过皮肤刺激导尿,但是没有一个能完全控尿,两个病人能下导尿管。其他两个手术带
来的好处一是肠功能,二是膀胱sensation。另,这9个病人中有一个 产生了垂足的后
果。除此外,没有其他的并发症发生。
从这些数据,可以看出,
1,反射弧形成的比例相当高,第一次,2/2, 第二次, 7/9 能自主小便。
2, 不能完全改善: 第一次,2/2停了药和导尿管;第二次,0/9可以完全自主导尿,2/9下了导尿管。
3, 其他好处: 肠功能,膀胱sensation
4, 并发症,或副作用,第一次, 0/2, 第二次: 1/9 垂足。
North American Studies
There have been attempts to replicate the Xiao procedure in
the United States. The first trial involved two traumatic SCI
patients—a ... 阅读全帖 |
|
D*******a 发帖数: 1723 | 27 科普一下肖氏反射弧和目前临床试验进展
1.脊柱裂,脊髓脊膜膨出,截瘫患者排尿困难,持续膀胱高压造成肾积水损害肾功能,
只能反复插拔尿管排尿,反复泌尿系统感染,最后尿毒症死亡占截瘫死亡的60-80%。所
以能否摆脱尿管就是患者生死的关键。
肖氏反射弧的手术目的就是能让患者拔掉尿管,能自主排尿。所以,判断这个手术成功
与否只有一个标准,就是能不能摆脱尿管自主排尿而且肾功能不受损。
2.肖传国自己声称手术成功率是87%。方舟子号称该手术治愈率为0
3. 看看美国人的临床试验结果。
William Beaumont Hospital, Kennith Peters主持的手术,1年后(2009年)的临床观察
结果发表在泌尿杂志上,9个患者有2个拔掉尿管,剩下7个有刺激皮节膀胱压升高
http://www.ncbi.nlm.nih.gov/pubmed/20639040
J Urol. 2010 Aug;184(2):702-7. Epub 2010 Jun 19.
Outcomes of lumbar to sacral nerve rerouting for spina bifida.
At ... 阅读全帖 |
|
D*******a 发帖数: 1723 | 28 科普一下肖氏反射弧和目前临床试验进展
1.脊柱裂,脊髓脊膜膨出,截瘫患者排尿困难,持续膀胱高压造成肾积水损害肾功能,
只能反复插拔尿管排尿,反复泌尿系统感染,最后尿毒症死亡占截瘫死亡的60-80%。所
以能否摆脱尿管就是患者生死的关键。
肖氏反射弧的手术目的就是能让患者拔掉尿管,能自主排尿。所以,判断这个手术成功
与否只有一个标准,就是能不能摆脱尿管自主排尿而且肾功能不受损。
2.肖传国自己声称手术成功率是87%。方舟子号称该手术治愈率为0
3. 看看美国人的临床试验结果。
William Beaumont Hospital, Kennith Peters主持的手术,1年后(2009年)的临床观察
结果发表在泌尿杂志上,9个患者有2个拔掉尿管,剩下7个有刺激皮节膀胱压升高
http://www.ncbi.nlm.nih.gov/pubmed/20639040
J Urol. 2010 Aug;184(2):702-7. Epub 2010 Jun 19.
Outcomes of lumbar to sacral nerve rerouting for spina bifida.
At ... 阅读全帖 |
|
m******x 发帖数: 809 | 29 欺负法官没学过英文?
2010年8月,美国的《泌尿学杂志》(The Journal of Urology)刊载的《脊柱裂病人
腰椎至骶骨神经重建手术》(Outcomes of Lumbar to Sacral Nerve Rerouting for
Spina Bifida)的结论应该是正面的,而不是像方舟子说的。
1年后新的反射弧可见于大多数病人。可以观察到排尿和肠道功能改善。 下肢无力,除
了一例,大多数具有自限性。需要更多的病例和更长时间的随访来评估这项新技术的风
险/效益比。
At 1 year a novel reflex arc with stimulation of the appropriate dermatome
was seen in the majority of subjects. Improvements in voiding and bowel
function were noted. Lower extremity weakness was mostly self-limited,
except in 1 subject with a persisten... 阅读全帖 |
|
D*******a 发帖数: 1723 | 30 你第一句话就撒谎,美国Beaumont Hospital, Kennith Peters主持的肖氏手术临床试
验,三年期7人6个拔掉尿管。
我实在不明白,明摆着的事实,你为什么要撒谎???
你是不是拿钱发帖,大家自己判断
发信人: Dogerella (Cherry), 信区: WaterWorld
标 题: 肖传国手术成功率87%,方舟子0,美国初期临床试验85.7%
发信站: BBS 未名空间站 (Fri Mar 9 22:15:34 2012, 美东)
科普一下肖氏反射弧和目前临床试验进展
1.脊柱裂,脊髓脊膜膨出,截瘫患者排尿困难,持续膀胱高压造成肾积水损害肾功能,
只能反复插拔尿管排尿,反复泌尿系统感染,最后尿毒症死亡占截瘫死亡的60-80%。所
以能否摆脱尿管就是患者生死的关键。
肖氏反射弧的手术目的就是能让患者拔掉尿管,能自主排尿。所以,判断这个手术成功
与否只有一个标准,就是能不能摆脱尿管自主排尿而且肾功能不受损。
2.肖传国自己声称手术成功率是87%。方舟子号称该手术治愈率为0
3. 看看美国人的临床试验结果。
William Beaumont Hospital,... 阅读全帖 |
|
b***n 发帖数: 13455 | 31 送交者: 羽矢 于 2012-04-04, 20:59:37:
回答: 周末一笑:Peters眼里的肖传国 由 羽矢 于 2012-04-04, 20:33:37:
2009年3月16日,脊柱裂协会举行脊柱裂研究及护理首届世界大会。会前的3月12日,
ACH医院在肖的指导下做了8例手术,其中包括唯一的一名10岁脊髓损伤患者Adam Byrum
。他是其中唯一的一例非“双盲”。
整整3年之后的今年3月12日,这名患者的结果公布了:“术后6个月有少许初步改善,
术后两年无临床改善”。继德国纽约大学的2例、Beaumont医院的2例、德国的8例脊髓
损伤肖氏手术临床试验全部失败后,这例失败无需惊讶。不过,值得注意的是,这是肖
氏手术术后进行探查的唯一一例:“肉眼观察发现吻合完整,未见电生理活动,神经未
从吻合处再生。”
术后探查发现虽然吻合完整,但神经却未再生,这对肖氏手术原理是致命一击。三家试
验方10余名脊髓损伤患者无一建立反射弧,已经有了神经解剖方面证明:异质神经不能
嫁接再生,肖氏弧原理错误。
两年前,脊柱裂协会首届世界大会期间,肖传国及其合作者们曾经着实风光了一下。肖
当年曾主持研... 阅读全帖 |
|
y******n 发帖数: 8667 | 32
Slide 7:
Six Months – initial optimism
Some improvement in bladder and bowel function
Possible initiation of voiding?
Urologists saw bladder contractions on urodynamic testing in the proper
dermatomal distribution to suggest bladder reflex
Two Years
No clinical improvement
No initiation of voiding with scratching
No contractions by urodynamic testing
和中文翻译一样啊?
LZ指造谣是哪里? |
|
G****o 发帖数: 124 | 33 你的功课还没有做好啊,看看这篇综述怎么评价肖氏反射弧吧:
7.1. Lumbar to Sacral Nerve Rerouting
Restoring bladder function in spina bifida by creation of a skin-
central nervous system bladder reflex arc via lumbar (L5 motor) to
sacral (S3) nerve rerouting has a reported success rate of 87% in 110
children in China [83]. Recently the one-year results of the first
North American trial were reported, with 7/9 (87%) of spina bifida
subjects having measurable increase in bladder pressure with L5
dermatomal stimulation (>10cm H2... 阅读全帖 |
|
t******n 发帖数: 2939 | 34 ☆─────────────────────────────────────☆
boilingsnow (沸腾的雪) 于 (Tue Mar 27 09:08:22 2012, 美东) 提到:
教主拉的屎总是时不时被教徒捡去吃。
全世界泌尿学界专业人士都不知道肖氏手术是非原创的,却被教主发现了!
☆─────────────────────────────────────☆
locarno (May the Force be with you) 于 (Tue Mar 27 09:18:51 2012, 美东) 提到:
即便你说的是真的,又怎么样?现在几乎说有新的医疗方式/药物,都是先动物实验,
难道这和你理解的常识/科学又不一致了?
☆─────────────────────────────────────☆
garnetcrow (kikicoco) 于 (Tue Mar 27 09:36:42 2012, 美东) 提到:
肘粉都是这种智障,现在有几个手术是发明最初就在人身上做,一次成功的?
☆─────────────────────────────... 阅读全帖 |
|
t******n 发帖数: 2939 | 35 ☆─────────────────────────────────────☆
itsbeautiful (poppop) 于 (Sat Apr 7 04:01:31 2012, 美东) 提到:
方粉一定要点开他提供的链接看啊,不要像国内部分不懂英语的人一样被耍
方舟子4月6日08:42 的新浪微博
3月12日美国阿肯萨斯儿童医院公布肖氏手术临床试验术后两年的结果,完全失败:术
后6个月有少许初步改善,术后两年无临床改善,抓挠不能引起排尿,尿动力学测试未
见膀胱收缩,电刺激无膀胱收缩,神经吻合处测量不到神经动作电位,未见电生理活动
,神经未从吻合处再生。http://t.cn/zOKR2TB
☆─────────────────────────────────────☆
Dogerella (Cherry) 于 (Sat Apr 7 04:29:32 2012, 美东) 提到:
我操,这也行?这个臭逼养的也忒无耻了吧
☆─────────────────────────────────────☆
itsbeautiful (poppop) 于 (Sat... 阅读全帖 |
|
c******k 发帖数: 237 | 36 顶一个KING的大作!
俺也添点砖加点瓦:
FileApp: Free. Open PDF, WORD, EXCEL, image files 的利器。例如 Dermatome Map
(See attached)
AHRQ: Free. Developed by HHS/AHRQ to assist primary care clinicians identify
the screening, counseling, and preventive medication services.
Merck: Free. Categorized by symptoms. 学习DDX 的利器 !!
Drug Pronunciations: $2
Microbiology Pronunciations: $2
Skyscape: 这个要$125,物有所值。我是PROGRAM给COVER的。
Pocket里的东西太多了, 所以手机和PDA最好是合二为一。目前用得最多是还是
epocrates and skyscape。价格上IPHONE的月费实际上比其他许多Smart phone还来得便宜。AT&... 阅读全帖 |
|
y***d 发帖数: 33 | 37 Sounds like the pattern described suggestsL5-S1 injury, which is consistent
with sciatic nerve. Would definitely consider nerve injury during IM
injection a possibility, particularly if the patient is thin. Would
prednison help in this case?
As far as conversion disorder goes, does anyone know if the symptom also
follow dermatomal distribution? My guess would be no. But who knows, maybe
the nurse is very good at her anatomy. |
|
A*******s 发帖数: 9638 | 38 You are right about the dermatomes. And there is no doubt the needle hit a
nerve.
Steroids may be helpful.
But here is my concern:
The sensory exam showed a very limited sensory loss on the foot. But the
motor exam indicated not only foot dorsiflexion but also plantar plexion
weakness. This does not make sense at all. A needle stick on the buttock
caused a complete sciatic motor nerve paralysis with relatively sensory
intact? Even a secondary compartment syndrome won't provide a picture like
th... 阅读全帖 |
|
C*****D 发帖数: 1299 | 39 有空能否学些基本知识再来胡乱指控。 方粉尽可上水版胡编。除了中国所谓专家和几
篇letter to editors, 从来没有peer revie w paper 说肖有问题。
肖和peters倒是分别发文,还写书。还有cme course。
再去上网看许多美国病人的评价,有许多spina bifida patient supporting groups
支持clinical trials。去那些美国人网站去看手术后病人怎么评价方粪spam他们网站。
许多方粪拿着这篇2009的综述,断章取义或英文太差,或别有用心。把一篇比较中性的
文章说成停用肖手术。
贴下文,是为the silenced majority,没有对方粪教育的义务。
Editor: Alan R. Cohen, MD Spring 2009
Xiao Procedure
Jeffrey P. Blount, MD, and Gerald Tuite, MD
At the conclusion of the recent First World Congress on Spina Bifida
Research and C... 阅读全帖 |
|
a******a 发帖数: 57 | 40 没有自己做体检,没有MRI影像学的数据,只能凭空说几句。
如果腰痛,腿痛可以用dermatome,myotome 的分布解释,并且在MRI上有concordant的
椎间盘突出(同侧,同一水平),才可以考虑手术。即使如此,也有很多医生只有在有
sensory或者motor deficit症状才手术,完全用痛作为手术指针有时并不一定是最佳方
案。术后由于瘢痕组织形成,神经根还有可能再次受到刺激。
这个手术本身就是开放做,也不算特别大。另外,要问清楚放钢板的指针是什么。要做
fusion?
:帮老妈问的。她现在60多了,坐骨神经痛两年前发的病,之前就是腰痛,腿脚发麻,
现在严重到全身痛,坐都不能坐,整天只能躺着,盗汗严重,怕风怕冷,严重影响生活
质量。家在南方某省会城市,在省里最好的医院骨科看了,说是因为椎间盘突出的位置
关系,不能做微创手术,要做开放性大手术,把突出的椎间盘拿掉,把相邻的两节椎骨
用钢板连接,伤口比较大,回复比较慢,风险相对较高。
: |
|