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全部话题 - 话题: conformal
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b******y
发帖数: 627
1
LZ wants a method that can monitor whether one conformation (active) is
preferentially stabilized versus others (inactive ones). No easy method,
though.
You might have to solve the structures of both wt and mutant and hope there
is difference. NMR is good at revealing conformational changes but your
protein might be too big for it. If you can design a good single molecular
FRET experiment, you might find more than one mode of conformations. In your
mutant, you see one of the conformation is more... 阅读全帖
t*******r
发帖数: 22634
2
来自主题: _GoldenrainClub版 - Re: 放心吧,一年内房价涨不了 (转载)
短期 Fed 敢大涨 conforming / super conforming 的贷款利率么?
现在的房子的 affordability 完全是靠低利率撑的。Fed 短期要是
大涨 conforming / super conforming 的利率的话,除非经济基本
面(失业率、工资水平)涨到能够 afford 高房价+高利率。否则,
俺估计需要有人借 Fed 豹子胆才成 …………
c*****u
发帖数: 1826
3
来自主题: _Xiyu版 - 好消息来了,刚刚收到的。
Ok, Conforming loans are $417K and below for the 1st loan. Anything larger
than $417K is a jumbo loan.
Conforming loans are protected by the government, if a homeowner defaults on
the loan, the gov. will make the lender whole. Therefore, less risk than
the Jumbo loan which is not 'insured' by the government.
Conforming loan rates are generally better than the jumbo loan rates.
If they raise the limit of conforming, that means more people with the 1st
loan amount less than what the new law states
h****d
发帖数: 1420
4
不少在哭求美国干涉军啊。打酱油的也不少。 哈哈
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Barack Obama
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Turbidsoul Chen - sofa?
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yuming xie - wow
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Rugger Ducky - So it is clearly going to be Obama/Biden eh?
11:13 AM
Hai Yan's... 阅读全帖
m**********e
发帖数: 12525
5
你学生物的,连什么叫李代数,什么叫conformal mapping都不知道,靠你妈的靠
成功的大洋航行,第一必须有祖国四大发明之一的指南针,第二必须至少了解用指南针
导航导致的对conformal mapping的需求
祖国的历史教科书,由于作者知识层次太低,一直强调指南针对大洋航行的作用,却
没有提及大洋航行对conformal mapping认识的需求
a*****1
发帖数: 3817
6
来自主题: USANews版 - trump懵逼了,trump轮集体被打脸
自己去看美国宪法
United States Constitution
From Wikipedia, the free encyclopedia
Jump to: navigation, search
United States Constitution
Constitution of the United States, page 1.jpg
Page one of the original copy of the Constitution
Created
September 17, 1787
Ratified
June 21, 1788
Date effective
March 4, 1789; 227 years ago
Location
National Archives,
Washington, D.C.
Author(s)
Philadelphia Convention
Signatories
39 of the 55 delegates
Purpose
To replace the Articles of Confederation (177... 阅读全帖
a*****1
发帖数: 3817
7
来自主题: USANews版 - trump懵逼了,trump轮集体被打脸
自己去看美国宪法
United States Constitution
From Wikipedia, the free encyclopedia
Jump to: navigation, search
United States Constitution
Constitution of the United States, page 1.jpg
Page one of the original copy of the Constitution
Created
September 17, 1787
Ratified
June 21, 1788
Date effective
March 4, 1789; 227 years ago
Location
National Archives,
Washington, D.C.
Author(s)
Philadelphia Convention
Signatories
39 of the 55 delegates
Purpose
To replace the Articles of Confederation (177... 阅读全帖
a*****g
发帖数: 110
8
来自主题: JobHunting版 - 贡献一道面试题
面的时候一时没想出来比较理想的方法
还请高手指点
Unsighed 30-bit integer B, 0 <= B < 2^30,
we say integer A conforms to integer B if A has bits set to 1 in all
positions where B has bits set to 1.
e.g. 00 0000 1111 0111 1101 1110 conforms to
00 0000 1100 0110 1101 1010
Write function which takes three 30-bit unsighed integer as input, and
returns the number of unsighed 30-bit integers that conform to at least one
of unsighed 30-bit A, B, C
e.g. A = 11 1111 1111 1111 1111 1111 1111 1001
B = 11 1111 1111 11... 阅读全帖
i****r
发帖数: 1803
9
来自主题: Living版 - 利率在降
Product Interest Rate APR Conforming 1and FHA Loans
30-Year Fixed 4.250% 4.433%
30-Year Fixed FHA 4.250% 5.087%
15-Year Fixed 3.500% 3.817%
5-Year ARM 2.875% 3.126%
5-Year ARM FHA 2.750% 2.948%
Larger Loan Amounts in Eligible Areas – Conforming and FHA.1
30-Year Fixed 4.250% 4.382%
30-Year Fixed FHA 4.250% 5.032%
5-Year ARM 3.125% 3.167%
Jumbo1 Loans – Amounts that exceed conforming loan limits1
30-Year Fixed 4.875% 5.01... 阅读全帖
d***y
发帖数: 231
10
偶们州的 JUMBO CONFORMING LOAN最大限额是42万3,只笔41万7千的CONFORMING LOAN
高个6千刀:(。。。偶像多贷个几万,不知道行不行?也不知道到底是怎么个WORK法
?谢谢。。。

conforming
d******n
发帖数: 2712
11
来自主题: Living版 - 请教房贷的利率
1.对于15年以上的贷款, down pay 25% 要和信用成绩740以上配合使用才行,两项都
满足的情况下有机会拿到最好的rate。
2. 417K是1 unit房屋的conforming loan上限,不太知道567K是什么。目前一般417K以
上729K以下是high balance或者叫做super conforming loan,rate比conforming稍高
。不同的county,high balance的上限会有不同。如果loan amount高于729K,那么就
是jumbo loan了,rate会高很多的。
b*d
发帖数: 9308
12
没有必要做两个loan. Jumbo conforming (high balance conforming)的贷款利率只比
conforming (<417K)的利率高0.25%。
f*******g
发帖数: 377
13
来自主题: Living版 - NJ这几天什么利率?
今天的行情应该是:
Conforming 417K
LTV<75% 30 year fixed: 3.375% no point, but with closing cost
Super Conforming 625.5K
LTV<75% 30 year fixed: 3.500% no point, but with closing cost
我今天锁了
Super Conforming
LTV<75% 30 year fixed: 3.625% no point, no closing cost, with 0.375
point credit back
w******t
发帖数: 16937
14
来自主题: Living版 - 申请房屋贷款时收入怎么算
你们要搞清楚什么是LTV的定义先。
The loan-to-value (LTV) ratio is a financial term used by commercial lenders
to express the ratio of a loan underwritten to a value of an asset
purchased.
The term is commonly used by banks and building societies to represent the
ratio of the first mortgage lien as a percentage of the total appraised
value of real property. For instance, if a borrower borrows $130,000 to
purchase a house worth $150,000 at a relative valuation, the LTV ratio is $
130,000/$150,000 or 87%.
Loan to... 阅读全帖
r****t
发帖数: 10904
15
来自主题: Living版 - 房贷找Wells Fargo最好
Wells Fargo has a relocation purchase program, can lock with 3.375% for
conforming loan even today. what's CF's conforming loan rates?

Conforming
Funding
r******d
发帖数: 1879
16
I am not sure if this is an coinstance. If you review the rate in the last
couple years ( I have a few years rate in my club for archieved history),
usually at the end of the year or the first quarter of the year, the rate is
really bad, comparing to other time.
The lowest rate for conforming 30 yrs is 3.125% but now it is 3.5%
The lowest rate for supconforming 30 yrs is 3.25-3.375, now is 3.625 to 3.75%
The lowest rate for conforming 15 yrs is 2.5% and now 2.75
The lowest rate for supconforing ... 阅读全帖
c**********e
发帖数: 1184
17
来自主题: Living版 - jumbo loan一定要20% down么
超过41万7的贷款应该叫做High-Balance或Super-Conforming,其上限依各州及County
而不同。超过Super-Conforming上限才是真正的Jumbo Loan。对于买房贷款,
- 如果是Super-Conforming的贷款:头款最低可做到10%;
- 如果是Jumbo Loan: 有银行可以接受最低15%的头款,但通常只有5/1或7/1 ARM。
如果你在CA、MD、TX或VA,可以和我们站内信箱联系。
h********e
发帖数: 224
18
后面的是APR。
as of 06/04/2013 11:00 AM Eastern
Product Interest Rate APR
Conforming 1and FHA Loans
30-Year Fixed 4.125% 4.294%
30-Year Fixed FHA 3.875% 5.015%
15-Year Fixed 3.125% 3.417%
5-Year ARM 2.375% 2.860%
5-Year ARM FHA 2.250% 2.942%
Larger Loan Amounts in Eligible Areas – Conforming and FHA.1
30-Year Fixed 4.250% 4.377%
30-Year Fixed FHA 4.000% 5.108%
5-Year ARM 2.625% 2.906%
Jumbo1 Loans – Amounts that exceed conforming loan limits1
30-Year Fixed 4.000% 4.112%
5-Year ARM
m****o
发帖数: 310
19
来自主题: Living版 - 贷款没批,求建议!
谢谢大家的回复。房子60万,20%首付,所以超过了417K。我的Broker提过Jumbo但是
没有提过super conforming,不知道我这个地区是否可以做super conforming。 如果
可以,super conforming也是和417K 同一个interest rate?
Broker说他熟悉的办理第2个贷款的公司turn down, he was surprised.The reason is
that we both work for < 1 yr. But is that the reason?
I don't understand if 420K can be approved, why 60K can not be approved?
Though, the 2nd mortgage has higher interest rate, 5%.
I******s
发帖数: 223
20
来自主题: Living版 - 请问到底可以贷到多少款
你这种情况贷款没有问题,不需要付车贷。综合原因如下:
1, 你这种情况是Conforming贷款, 贷款银行基本都是打包卖给Fannie Mae 或者
Freddie Mac,Fannie Mae和Freddie Mac 对Front end ratio都没有要求。Fannie Mae
对Back end ratio 的要求Guideline上是45%, 但是有是综合别的条件很好的话, 50%
以下也有可能approve。 Freddie Mac 在guideline上对Back end ratio 没有要求,
但是以我们最近的经验也是50%。
2,所谓的Front end ratio是一些贷款银行为了更好的保护自己在Fannie Mae和
Freddie Mac的基础上加的要求。对于conforming 贷款, 现在有些贷款银行对Front
end ratio 没有要求, 有一些要求41%或者以下。你所说的28%,36%等, 对
conforming 贷款不apply。以前subprime贷款很多银行有这样的要求, 现在很少听说
了。
3,在极端情况下, 你现在付车贷款的钱以后贷款的... 阅读全帖
c*****4
发帖数: 900
21
来自主题: Living版 - 闲话房贷-怎么做cashout refinance
一. 什么是cash-out refinance?
Cash-out refinance就把一个房子的总价值扣除已经有的贷款金额的部分(equity)作
为抵押拿cash出来。比如说,有个房子买的时候成交价是$600K,贷款了$480K,那么你
的equity就是$120K,过了三年以后,房子的市价涨到了$1M,房主需要用钱,那么就可
以从$520K的equity中拿一部分出来,比如说,拿出来了$200K,且当时原来的房贷剩的
balance是$400K,那么新的总贷款金额就是差不多$600K,申请cash-out refinance的
银行会用这一个大贷款付清原来的贷款,剩余的就是可以拿出来的现金,原来的银行的
贷款被close掉,只剩一个大的。
二. 什么样的房子可以做cash-out refinance?
大体上普通的1-4 unit的single family house, multi-unit house, townhouse,
condominium都可以做cash-out refinance,只不过有些lender有些特殊的规定,例如
投资房的condo不能做cash-o... 阅读全帖

发帖数: 1
22
没有这个规定,现在低于$424,100(不是417K)的贷款金额叫做conforming loan,高
于这个金额的要么是conforming high-balance要么是jumbo loan,也许你的loan
officer在评估了你的信息之后告诉你只能做conforming而不能做jumbo,但是这也只跟
收入之类的有关,和ARM能不能高于$417K没关系.
u********e
发帖数: 4950
23
来自主题: Stock版 - FA BAC
On Sep 30th 2010:
* Book value per share: $21.17
* Tangible book value per share: $12.91
* Earning Asset: $1902 billion ( Total Asset: $2456 billion)
* Deposit: $982 billion
* Shareholder Equity: $232 billion
About "Mortgage banking"
* Total mortgage service fee: $3.7 billion ( typically 25 - 45 basis points
of the unpaid principal balance)
* about 45% are non-conforming loans, 55% sold to Fannie Mae
"Mortgage Banking" Risk analysis:
* if 20% of the non-conforming were forced to be boug... 阅读全帖
f******e
发帖数: 599
24
来自主题: Immigration版 - NSC 485 RFE,请问关于结婚公证
第一次的结婚公证没有附conformity statement,被RFE了。但那个版本的公证,公证
处就没有提供conformity statement。于是最近又从公证处request了一份新的,含
conformity statement的公证。现在准备提交RFE材料。请问大家:结婚公证:前几页
是结婚证原件的复印件,是否需要附上?这个是中文的,如果附上,是否需要找个人
translate一下? 还是无需附这几张,直接上公证处公证的那几页即可?
非常感谢!~
W***o
发帖数: 6519
25
今天终于在信箱里收到RFE材料,但是不太明白到底还要补啥,因为当初在寄485的时候
已经包括了 公证书/Notarial Certificate。下面是RFE材料的原话:
The U.S. Department of State (DOS) provides the following information
regarding marriage certificates from China:
Marriage - Available in the form of notarial marriage Certificates (Jie
Hun Gong Zheng [ or Zheng Ming] Shu) or death certificates which are
generally reliable.
While the record contains a page of your notarial marriage certificate, the
document is not complete. Neither is there a complete certif... 阅读全帖
l*****e
发帖数: 284
26
来自主题: Boston版 - 房市2013 vs. 2005
麻州的房市在曾2005年达到了历史高点。记得2005年五月的一个星期天下午,我在
Coldwell Banker Newton办公室坐班,一个资深经济进来说,“简直发疯了,今天
Newton有4百多个Open House!” 当时听了之后隐隐的感觉房市可能要拐弯了。
拿Newton为例,今年Newton房市到目前为止成交991单(包括公寓,单家庭和多家庭)
,2005年总成交978单,成交量有可比性。区别是2013年的今天Newton待售的房源只有
95个,2005年夏天的待售房源近600个,冬天也有300多个。任何一个市场的价格走势完
全取决于供需关系。在地产行业有个术语叫吸收率(absorption rate),直白的说就
是市场消化待售存货的速度。一个正常平衡的房市场,吸收率是5-7个月,即市场有在5
到7个月内消化掉现有存货的能力。Newton最近30天签了offer和买卖合约的房源有101
单,待售房源95个,不言而喻市场对的房源需求到了12月的淡季还是很强。从现有房源
角度看2014年还会是卖方市场。
就业市场和房贷市场是影响房市的最大两个因素。政府和权威机构每个月都公布就... 阅读全帖
y*****y
发帖数: 413
27
5 year arm, conforming loan (<=417k) :
Best Rate is 2.75
7 year arm, conforming loan (<=417k) :
Best rate is 3.125
5 year arm, Super conforming loan (>417k and <=729k) :
Rate is 3.25 to 3.375 (up to loan amount) 这个rate只针对SFH, 针对condo的
可能会高, 要单独check。
Lender will credits back to cover your total closing cost (maybe most
of your closing cost)
Here is the qualification:
1) Loan to Value is 75%
2) FICO(信用分数): >=740
具体细节站内联系。
y*****y
发帖数: 413
28
来自主题: SanDiego版 - *** 5年arm 最好利率 2.75 ***
现在想做或打算做5年ARM的,利率相当低了!
5 years arm, conforming loan (<=417k) :
Best Rate is 2.75
7 years arm, conforming loan (<=417k) :
Best rate is 3.125
5 year arm, Super conforming loan (>417k and <=729k) :
Rate is 3.0 to 3.375 (up to loan amount) 这个rate只针对SFH, 针对condo的
可能会高, 要单独check。
Lender will credits back to cover your total closing cost (maybe most
of your closing cost)
Here is the qualification:
1) Loan to Value is 75%
2) FICO(信用分数): >=740
30年的 4.75
具体个人能拿到的利率要根据当时的情况和你个人具体的条件。
有意者站内联系。
d***y
发帖数: 263
29
来自主题: SanFrancisco版 - [合集] 请问一个second mortgage的问题
☆─────────────────────────────────────☆
lopt (NextStep) 于 (Thu Apr 3 21:25:10 2008) 提到:
比方说我的房子market value 500k,现有200k的30年fixed mortgage,5.25% rate。
我想再借100k出来,但是现在的rate没有那么好了,所以不想refi。
怎么样才能借个second mortgage呢?HELOC肯定是不划算。如果我再借100k,两个
mortgage加起来还是少于conforming的limit,那么这个second mortgage能算
conforming吗?
多谢!
☆─────────────────────────────────────☆
tonyxu (无斋主人) 于 (Thu Apr 3 21:43:06 2008) 提到:

HELOC is HELOC, nothing to do with conforming.
Since your CLTV is low,you shall be able to get
r******d
发帖数: 1879
30
来自主题: SanFrancisco版 - 房贷利率越来越坏了
oops. my mistake. (blushing)
15Yr Fixed Conforming (<=417K), 4.25%
thank you for point that out.
发信人: gas (consume me), 信区: SanFrancisco
标 题: Re: 房贷利率越来越坏了
发信站: BBS 未名空间站 (Thu Jun 3 15:41:23 2010, 美东)
15Yr Fixed Conforming bi Super conforming gao?
r******d
发帖数: 1879
31
No Point No Fee, Refinance And New Purchase Loan Rate
(all based on full impound and 30 day lock period)
Conforming(<=417K, LTV80, SFR, 740+) Refinance
5yr ARM, 3.25
7Yr ARM, 3.625
10Yr ARM, 4.375
15Yr Fixed, 4.25
30Yr Fixed, 4.625
Conforming(<=417K, LTV80, SFR, 740+) Purchase
5yr ARM, 3.25
7Yr ARM, 3.625
10Yr ARM,4.375
15Yr Fixed, 4.25
30Yr Fixed, 4.625
Super Conforming(<=729K, SFR, 740+) Refinance
5Yr ARM(LTV75),3.5
7Yr ARM(LTV75), 4.375
10Yr ARM(LTV75), 4.625
15Yr Fixed(LTV80),4.25
30Yr Fixed
j********i
发帖数: 913
32
来自主题: SanFrancisco版 - 3.125% 5/1ARM 600k
PF永远是天下最精明, 最刁钻的银行,别人降,它反而涨,别人涨, 它一定有几个
Program 在那个时间段内, 天下无敌。我们和它斗了这么多年, 可以说, 对它的规
律太了解了。 这就是我们永远居安思危, 不会像没经验的broker 碰到好时, 扰乱市
场, 碰到不好时,素手无策的。
PF 确实于6/2日突然提升了5/1 and 7/1 ARM 的利率,特别是7/1 ARM--Conforming Loan,现在purchase 的rate至少3.125% or 3.25%, 我们很Lucky,几个purchase 7/1 ARM 都在15天之内把 final docs 送到title, 而且拿到2.875% 的利息,No Points, No costs.
For 5/1 ARM--super Conforming, $600K, as long as LTV < 75%, even now, 2.875%, no points, no costs, should be 100% no Problem!
我们还close了一批2.625%的5/1 Super Conforming,... 阅读全帖
g****n
发帖数: 3313
33
URGENT: URGENT:
If you are residing in Cupertino Union School District or Fremont Union High
School District, this is extremely important to you!
Call to every one to attend the Cupertino City Council meeting tonight (Nov.
10) at 6:45pm City Hall Community Hall in Cupertino.
Cupertino city is evaluating a proposal of adding 4000 apartment units, if
this proposal is approved by the Cupertino City Council, both CUSD and FUHSD
Districts will be negatively impacted, resulting in bigger number of
stu... 阅读全帖
c*****4
发帖数: 900
34
一般来说,低于$625.5K的贷款,DTI最高不能超过50%.
贷款一般分三档,低于$417K的(conforming),介于$417K到$625.5K的(conforming
high balance)以及高于$625.5K的(jumbo),不同的银行差别很大,有的银行优势是
jumbo,那么可能比较大的贷款能拿到的利率比较好;有的银行则是conforming比价好
一点。
j********i
发帖数: 913
35
来自主题: SanFrancisco版 - 求 refinance rate
现在这种情况, 尤其是 Super Conforming, 30年和5/1, 7/1 的差别最多才0.5-0.
75%, 这点小便宜根本不值得占。
这位说啦, 我要是5-7 年之内卖房子咋办? 不是亏了吗?
如果现在30-year可以做到3.5%, no points, no costs, 我都建议你根本不用卖房子!
因为你只要租金能有 2500 以上, 这在San Jose, 几乎是逼着眼睛的事。 租金替你
养房子, 试看20-30年以后, 孩子长大了, 会非常感谢老爸,老妈的英明远见的。
而且根本不影响你换大房子, 只要有 20% 的down payment。 我们完全可以用
departure house 的可能租金 来计算DTI. 非常容易的事。
所以, 现阶段,做Conforming 和super Conforming 的客人, Fixed rate 才是最明
智的选择。
x5
发帖数: 27871
36
来自主题: PhotoGear版 - 11/12款Jetta有人买妹?
看所在地区了
原来417000以上的叫jumbo, 一下的叫conforming
后来房事垮了,弄了个super conforming出来,super conforming的上限依据各个州的
平均房价来算
T*********I
发帖数: 10729
37
来自主题: WaterWorld版 - 方教主一向如此,理论决定一切
Re [亦明早就总结过,教主写东西靠铺点的基本上是抄的]
Found it: http://www.bullogger.com/blogs/antixys/archives/241060.aspx
**********************************************
亦明:不知道“脸红”的方舟子
天涯博客
不知道“脸红”的方舟子(一)
在分析方舟子“科普”转基因问题时,我曾把方氏的“科普”定性为“科唬”:
“以科学的名义”唬弄人、吓唬人、瞎诈唬。
对于这个定性,方舟子本人是默认的,因为他从来就没有敢对这个论断发出一丝声
响----虽然他对我恨之入骨。但时至今日,方舟子仍旧不乏跟班帮闲,他们之中也许有
人会说:就算你亦明说得对,那也仅仅能够证明方舟子在转基因问题上搞科唬。他科普
的领域五花八门,难道都是科唬吗?这就是本文要解答的一个问题。
方舟子自称是“无业游民”,因此导致了社会上对他“何以为生”发生了怀疑。几
年前,方博士还可以得意洋洋地挥挥手中的那张“美国生物信息公司科学家”名片把疑
问驱散。而如今,虽然方舟子的这个名片本身又变成... 阅读全帖
t*********r
发帖数: 122
38
[原帖已被版主误删] 」现重新打字贴出:
和合本中文圣经对华语圣徒真理生命的追求无容置疑,但它翻译的缺憾、模糊及属灵上
粗造已经越来越成为华语圣徒追求的障碍。
让我们一一来看:
1. 约翰福音 4:24
KJV: God is a Spirit: and they that worship him must worship him in spirit
and in truth.
直译: 神是灵:那些敬拜祂的必须在灵里和在真实里(或真理中)敬拜。
NIV: God is spirit, and his worshipers must worship in spirit and in truth.
直译: 神是灵,并且祂的敬拜者必须在灵里和在真实里(或真理中)敬拜。
ASV: God is a Spirit: and they that worship him must worship in spirit and
truth.
直译: 神是一个灵: 并且那些敬拜祂的必须在灵里和真实里(或真理中)敬拜。
NLT: For God is Spirit, so those who worshi... 阅读全帖
R*o
发帖数: 3781
39
来自主题: TrustInJesus版 - What Love is This?(24) hijack the Reformation
Good Intentions Gone Astray
No one has ever been as successful as John Calvin at totalitarian imposition
of "godliness" upon a whole society. And therefore no one has proved as cle
arly as he that coercion cannot succeed because it can never change the hear
ts of men. Calvin's theology as laid out in his Institutes denied that unreg
enerate man could choose to believe and obey God. Apparently he was ignorant
of the commonsense fact that genuine choice is essential if man is to love
and obey God ... 阅读全帖
d*********e
发帖数: 3835
40
Citizenship Requirement: U.S. Citizen
Preference will be given to local candidates.
Responsibilities:
• Interacts with Maintenance and Paint Supervisors, Paint Leads, and
maintenance and paint technicians performing aircraft maintenance, servicing
, ground handling and painting functions.
• Perform and document multiple daily technical inspections
• Aircraft inbound inspections
• In-process maintenance and paint inspection
• Placard conformity inspections
• Ai... 阅读全帖

发帖数: 1
41
要是把这作为关键拿来单练,可说的话就太多了:你的实验不work?你实验室的器材药
品各种条件没有允许protein-dna complex形成。或者:你的蛋白根本没有处在native
conformation。或者:你断定你的蛋白fold到native conformation了?要实验work蛋
白就不能处在native conformation,必须得是intermediate 或者transition state。
a*i
发帖数: 1652
42
来自主题: MedicalDevice版 - ISO 13485
http://en.wikipedia.org/wiki/ISO_13485
ISO 13485 is an ISO standard, published in 2003, that represents the
requirements for a comprehensive management system for the design and
manufacture of medical devices [1][clarification needed]. This standard
supersedes earlier documents such as EN 46001 and EN 46002 (both 1997), the
ISO 13485 published in 1996 and ISO 13488(also 1996).
While it remains a stand-alone document, ISO 13485 is generally harmonized
with ISO 9001. A fundamental difference, howe... 阅读全帖
a*i
发帖数: 1652
43
来自主题: MedicalDevice版 - Corrective and Preventive Action (CAPA)
http://en.wikipedia.org/wiki/Corrective_and_preventive_action
Corrective and preventive action (CAPA, also called corrective action /
preventive action) is a concept within good manufacturing practice (GMP).
CAPA focuses on the systematic investigation of discrepancies (failures and/
or deviations) in an attempt to prevent their recurrence (for corrective
action) or to prevent occurrence (for preventive action). To ensure that
corrective and preventive actions are effective, the systematic
inves... 阅读全帖
f**d
发帖数: 768
44
来自主题: Neuroscience版 - eBook: From computer to brain
这是一本计算神经科学的优秀著作,全文拷贝这里(图和公式缺),有兴趣的同学可以
阅读
如需要,我可以分享PDF文件(--仅供个人学习,无商业用途)
From Computer to Brain
William W. Lytton
From Computer to Brain
Foundations of Computational Neuroscience
Springer
William W. Lytton, M.D.
Associate Professor, State University of New York, Downstato, Brooklyn, NY
Visiting Associate Professor, University of Wisconsin, Madison
Visiting Associate Professor, Polytechnic University, Brooklyn, NY
Staff Neurologist., Kings County Hospital, Brooklyn, NY
In From Computer to Brain: ... 阅读全帖
a**y
发帖数: 6501
45
来自主题: _aily版 - Re-Fi汇总
Mortgage Type:Conforming(<417K), Super-Conforming(<523K),
Jumbo conforming (<729k), jumbo, super jumbo
g********n
发帖数: 2314
46
原来是'Performance profiling' could help to catch cheater 现在是 '
Performance profiling' could help to dispel doubts.
Why great Olympic feats raise suspicions
'Performance profiling' could help to dispel doubts.
Ewen Callaway
01 August 2012 Corrected: 03 August 2012
Chinese swimmer Ye Shiwen broke the world record for the women's 400-metre
individual medley event at the Olympic Games on 28 July.
L. NEAL /AFP / GETTY IMAGES
Article tools
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At the Olympics,... 阅读全帖
w****2
发帖数: 12072
47

Of course.
There are two kinds of 民主:
1) 形式民主 (a procedure is followed to show the decision conforms to most
of people's opinion),
2) 实质民主 (the decision conforms to most of people's opinion).
Mao did not set up a real 形式民主 (人民代表大会 is not counted).
Mao tried to set up a 实质民主:
a) people's voice can be easily heard,
b) people within a unit form a committee of the unit, and the committee make
decisions for some problems with the unit.
But the 实质民主 was only partially set up. Moreover, the most impo
w****2
发帖数: 12072
48
【 以下文字转载自 ChinaNews 讨论区 】
发信人: wlwl12 (月夜逃亡), 信区: ChinaNews
标 题: Re: 对待老毛,还是要功是功过是过,分开来说比较好
发信站: BBS 未名空间站 (Wed Apr 28 21:39:08 2010, 美东)
Of course.
There are two kinds of 民主:
1) 形式民主 (a procedure is followed to show the decision conforms to most
of people's opinion),
2) 实质民主 (the decision conforms to most of people's opinion).
Mao did not set up a real 形式民主 (人民代表大会 is not counted).
Mao tried to set up a 实质民主:
a) people's voice can be easily heard,
b) people within a unit form a committee of t
C********n
发帖数: 6682
49
来自主题: Military版 - 朱学勤抄袭事件 ---1
发信人: Isaiah (SKIASONARANHR), 信区: Reader
标 题: 朱学勤——学术界的又一个“汪晖”?(全文)
发信站: 水木社区 (Thu Jul 8 14:11:42 2010), 站内

自有良心的媒体和学术界人士深入开展揭批学霸、学奸、学贼汪晖的工作以来,成绩突
出,形势喜人。到了今天,可以说汪氏的问题已经无所逃罪天下,可以立刻盖棺论定,
直接开除出学界了。笔者生性愚钝,见事不明,不仅未能参与到这个伟大的运动中去,
最初还一再为汪某辩护,是非颠倒,黑白不分,如今思之,惭恨不已。如今总算如梦初
醒,回头是岸,想要为打汪晖运动出一把力,但揭批汪晖的,从林毓生这样的老牌名宿
,到王彬彬等中坚学者,以及vivo等青年才俊不计其数,宏文妙笔如漫天星斗,又如黄
河泛滥,一发而不可收拾。多笔者一个不多,少笔者一个不少。好在一个汪晖倒下去,
千百个汪晖站起来。像汪晖这样隐藏得很深的伪学者名流还是很多的。在打倒汪晖后,
深入揭批学界问题已经成为刻不容缓的急务,笔者愿为此略尽绵薄之力。今天要谈的就
是又一个汪晖式的伪学者——朱学勤!
以下是笔者花了两小时时间查找和校对朱... 阅读全帖
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