p*****e 发帖数: 290 | 1 Other and past predictions:
Biomolecular motors: Vale, Sheetz, Spudich, Brady
Unfolded protein response: Walter, Mori
Soft lithography and microfluidics: Whitesides, Quake
Chaperonins: Horwich, Hartl, Lindquist, Ellis
Polymers: Frechet, Matyjaszewski, Wang, Willson
Electrochemistry/bioinorganic: Bard, Gray, Lippard
Single-molecule spectroscopy: Moerner, Orrit
Solar: Grätzel, Nocera
DNA synthesis: Caruthers
Next-gen sequencing: Webb, Craighead, Klenerman, Church …
Super-resolution optical mi... 阅读全帖 |
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发帖数: 1 | 2 求审稿机会,
[email protected]/* */
以下方向
(1) structural biology, Cryo-Electron Microscopy, Cryo-electron Tomography
(2) structure and function of motor protein, myosin, actin
(3) Structure and function of muscle related field
(4) Structure and function of Virus, Especially HIV virus
(5) chaperonin
Many thanks |
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F******y 发帖数: 1988 | 4 Trends in Biochemical Sciences, Volume 19, Issue 12, 543-548, 1 December
1994
doi:10.1016/0968-0004(94)90058-2
Cystosolic chaperonin subunits have a conserved ATPase domain but diverged
polypeptide-binding domains
Suwon Kima, Keith R. Willisonb and Arthur L. Horwicha |
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Z********9 发帖数: 17 | 5 Crystal structure of the open conformation of the mammalian chaperonin CCT
in complex with tubulin
on NSMB |
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s******y 发帖数: 28562 | 6 细胞里面的蛋白有各种各样的条件保护着,比方说chaperonin,以及大量的其他蛋白,
所以一个单独的蛋白品种不是那么容易变性,而且细胞里的蛋白是在不停地合成中的,
变性后的东西很快就会被清除掉。
但是在试管里的东西就没有这些保护所以会比较脆弱。而且一旦某个蛋白在体外变性了
,因为没有体内的清除机制,很容易就造成沉淀,然后导致那些本来没有变性的蛋白也
出于疏水力的作用而共沉淀下来。 |
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l**********1 发帖数: 5204 | 7 韦氏拼音
Chiu, Wah 趙華
香港出来的
Alvin Romansky Professor of Biochemistry, National Center for
Macromolecular Imaging, Baylor College of Medicine, Houston
//www.bcm.edu/biochem/?PMID=3715
http://www.mitbbs.ca/article_t1/Biology/31665667_0_4.html
or
【Southern Wanwan 訊】在結構生物學蓬勃發展的大趨勢下,台灣已有數個單位設置冷
凍電子顯微鏡核心設施。為能結合臨床與基礎的研究成果以推展結構生物學為基礎的臨
床診斷與治療科技,國立成功大學口腔醫學研究所特別邀請結構生物學家及冷凍電子顯
微鏡專家趙華院士訪台,並在成大演講「Chaperonin-based therapeutics
development for Huntington Disease」,透過演說、論壇與實地訪查促進雙方學術交
流。
//news.secr.ncku.edu.tw/fil... 阅读全帖 |
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