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全部话题 - 话题: adenylyl
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c**l
发帖数: 121
1
来自主题: Biology版 - Paper help, thank you very much!
Crystal structure of the catalytic domains of adenylyl cyclase in a complex
with
Gsalpha.GTPgammaS.
Tesmer JJ, Sunahara RK, Gilman AG, Sprang SR.
Science. 1997 Dec 12;278(5345):1907-16.
Crystal structure of the adenylyl cyclase activator Gsalpha.
Sunahara RK, Tesmer JJ, Gilman AG, Sprang SR.
Science. 1997 Dec 12;278(5345):1943-7.
GAP into the breach.
Sprang SR.
Science. 1997 Jul 18;277(5324):329-30.
请发到邮箱 c*****[email protected], 非常感谢!
s********o
发帖数: 21
2
来自主题: MedicalCareer版 - Step1 NBME#11 一题求教~
29. A previously health 6 month old boy develops fever and severe paroxysmal
barking coughing. He has not had any immunizations. His leukocyte count is
30,000/mm3 (70% lymphocytes). Neutrophil chemotaxis and oxidative metabolism
are defective due to increased activity of which of the following enzymes?
A. adenylyl cyclase
B. MPO
C. NADPH oxidase
D. Phospholipase C
E. Protein Kinase C
论坛上不少人选A,并且说是B. Pertussis 感染,请问大家什么看法啊?
我自己觉得:
1. 如果确定是Pertussis感染,adenylyl cyclase (AC)的activity就会up-
regulated.... 阅读全帖
f******g
发帖数: 1003
3
肖俊宇
1. Tagliabracci VS#, Xiao J#, Dixon JE. Phosphorylation of Substrates
Destined for Secretion by the Fam20 Kinases. Biochem Soc Trans. 2013 Aug 1;
41(4):1061-5. (# Equal contribution).
2. Xiao J, Tagliabracci VS, Wen J, Kim SA, Dixon JE. Crystal Structure of
the Golgi Casein Kinase. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):
10574-9.
6. Xiao J, Engel JL, Zhang J, Chen MJ, Manning G, and Dixon JE.
Structural and functional analysis of PTPMT1, a phosphatase required for
cardiolipin... 阅读全帖
r****i
发帖数: 323
4
来自主题: Biology版 - paper help !!
J Recept Signal Transduct Res. 2010 Dec;30(6):372-5. Epub 2010 Aug 23.
On the roles of Mg in the activation of G proteins.
Birnbaumer L, Zurita AR.
Laboratory of Neurobiology, National Institute of Environmental Health
Sciences, NIH, DHHS, Research Triangle Park, NC27709, USA. birnbau1@niehs.
nih.gov
Abstract
In this review, we highlight the evolution of our knowledge about the way Mg
(2+) participates in the activation of heterotrimeric G proteins, beginning
with its requirement in hormonal sti... 阅读全帖
s***a
发帖数: 671
5
来自主题: Biology版 - 一个蛋白 叫 zhangfei
还有个蛋白叫yotiao.
The A-kinase anchoring protein Yotiao binds and regulates adenylyl cyclase
in brain.
上次有人来我们这做报告,底下的中国人都笑翻了。
l****0
发帖数: 84
6
来自主题: Biology版 - paper help
Interactions between adenylyl cyclase, CAP and RAS from Saccharomyces
cerevisiae.
Mintzer KA1, Field J.Cell Signal. 1994 Aug;6(6):681-94.
Thanks in advance.
b****5
发帖数: 504
7
来自主题: MedicalCareer版 - 请教一道 NBME 12 question
请教:
A previously healthy 6-monthold boy is brought to the physician because of a
cough for 1 week, initially he had a low-grade fever, sneezing, congestion,
and runny nose, He then developed a dry intermittent cough, The parents now
note that with any startle the baby chokes and gasps, He has not had any
immunizations. Physical examination shows paroxysms of "machine gun" -like
coughing with a forced expiratory grunt at the end of coughing, Leukocyte
count is 30,0001mm3 (70% Iymphocytes). Neutro... 阅读全帖
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